{"id":"W2801556350","doi":"10.1007/s00018-018-2821-0","title":"Micromanaging freeze tolerance: the biogenesis and regulation of neuroprotective microRNAs in frozen brains","year":2018,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"microRNA; Neuroprotection; Biology; Cell biology; Biogenesis; Signal transduction; Downregulation and upregulation; Extracellular; Neuroscience; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001269608,0.0002056671,0.0001978727,0.0001721676,0.0002494658,0.0003375732,0.0002203999,0.000235403,0.001236347],"category_scores_gemma":[0.0001735572,0.0001349163,0.0001821417,0.000086058,0.0004082083,0.0004401231,0.0002767325,0.0005232976,0.0001453645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003065448,"about_ca_system_score_gemma":0.0002530849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007243376,"about_ca_topic_score_gemma":0.001904637,"domain_scores_codex":[0.9999366,0.000006473155,0.000003485028,0.00002153009,0.00001069614,0.00002125455],"domain_scores_gemma":[0.9999242,0.000007638173,0.00002364093,0.000009286649,0.00001605287,0.00001917345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002847294,0.00001658426,0.0007929796,0.00003811156,0.00000947163,0.00009720275,0.0001053733,0.00004913745,0.9937387,0.0005791397,0.0001289109,0.004159658],"study_design_scores_gemma":[0.00003134655,0.0005225829,0.06617456,0.00003627175,0.0000586063,0.0006392613,0.0009280512,0.0009246874,0.9249818,0.001878363,0.003800926,0.00002365575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937005,0.002228973,0.002595499,0.0001544092,0.00006760156,0.00001107292,0.00009126484,0.00003740822,0.001113278],"genre_scores_gemma":[0.9958006,0.0009177772,0.001077595,0.00008461482,0.00001506617,0.00002605893,0.0001154697,0.00002162316,0.001941291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236347,"threshold_uncertainty_score":0.004136026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01082352399057914,"score_gpt":0.2073390380661246,"score_spread":0.1965155140755455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}