{"id":"W2801562008","doi":"10.1016/j.humpath.2018.04.004","title":"SWI/SNF protein expression status in fumarate hydratase–deficient renal cell carcinoma: immunohistochemical analysis of 32 tumors from 28 patients","year":2018,"lang":"en","type":"article","venue":"Human Pathology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Calgary Laboratory Services","funders":"","keywords":"SMARCB1; SMARCA4; ARID1A; SWI/SNF; Cancer research; Clear cell; Renal cell carcinoma; Medicine; Papillary renal cell carcinomas; Pathology; Biology; Chromatin remodeling; Mutation; Chromatin; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001301997,0.0001811506,0.0003342249,0.0001504394,0.00007214332,0.000007478028,0.0001982854,0.0001956924,0.0001115949],"category_scores_gemma":[0.0000301975,0.0001727467,0.0001289479,0.0001916595,0.0002120705,0.000003367213,0.000166105,0.0001235244,0.000007864558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000517984,"about_ca_system_score_gemma":0.0000605425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002752351,"about_ca_topic_score_gemma":0.0001147127,"domain_scores_codex":[0.9984128,0.0001366103,0.0004547871,0.0005235864,0.0001490276,0.0003231754],"domain_scores_gemma":[0.9990462,0.000007253594,0.0002277598,0.0005357207,0.0001175689,0.00006549995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001381976,0.0002183526,0.01245523,0.00001162437,0.00002280327,0.000008528195,0.0002705098,0.0001047434,0.9863163,0.000003218011,0.000307003,0.0001434555],"study_design_scores_gemma":[0.001177259,0.0005021436,0.04310031,0.00002551066,0.00008207536,7.794162e-7,0.00005335721,0.000341355,0.9542522,0.00004775009,0.0002104991,0.0002067398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998289,0.0005149123,0.000223956,0.000003705273,0.00005652734,0.0001788172,0.000228353,0.000007687601,0.0004970749],"genre_scores_gemma":[0.9973809,0.000005710464,0.0004192475,0.00004032814,0.00007398066,0.00003669751,0.001920683,0.00001823422,0.0001042577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03206411,"threshold_uncertainty_score":0.7044405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008453505505629353,"score_gpt":0.2483374158677204,"score_spread":0.239883910362091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}