{"id":"W2801615935","doi":"10.1016/j.biochi.2018.04.024","title":"Sabellastarte magnifica Carboxypeptidase Inhibitor: The first Kunitz inhibitor simultaneously interacting with carboxypeptidases and serine proteases","year":2018,"lang":"en","type":"article","venue":"Biochimie","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; International Union of Biochemistry and Molecular Biology","keywords":"Proteases; Biochemistry; Serine; Carboxypeptidase; Elastase; Serine Proteinase Inhibitors; Serine protease; Carboxypeptidase A; Chemistry; Trypsin; Enzyme; Pancreatic elastase; Protease; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001925102,0.0006039329,0.0005119048,0.0002730924,0.0002886926,0.0005296228,0.0002627286,0.0004484968,0.0005002586],"category_scores_gemma":[0.0001469982,0.0001508389,0.0002764714,0.0001990003,0.0002264691,0.0002247862,0.0003570236,0.000657512,0.0003152938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006670449,"about_ca_system_score_gemma":0.0004577082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002283961,"about_ca_topic_score_gemma":0.002059153,"domain_scores_codex":[0.9998292,0.00001799415,0.000007930685,0.00003144817,0.00006161871,0.00005171816],"domain_scores_gemma":[0.9998983,0.000009779541,0.00002247527,0.0000100837,0.00002377649,0.00003556539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001300545,0.00001728066,0.0003233923,0.00004380786,0.000009039177,0.00003749312,0.00000821784,0.00006627235,0.9956177,0.00007565408,0.00009440919,0.003576715],"study_design_scores_gemma":[0.000006175405,0.00007394959,0.001667138,0.000003184321,0.00001315696,0.0001422273,0.0000104871,0.0004049223,0.9928843,0.00002015015,0.004771101,0.000003288352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9611892,0.01515751,0.01677591,0.000633072,0.0001696257,0.00007853694,0.0005505274,0.0003383937,0.005107386],"genre_scores_gemma":[0.9750795,0.002596724,0.0117952,0.0001657293,0.0000381321,0.00003308583,0.001004344,0.00004368504,0.009243542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002283961,"threshold_uncertainty_score":0.004839838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01028859211875929,"score_gpt":0.2389415455831807,"score_spread":0.2286529534644214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}