{"id":"W2801801585","doi":"10.1016/j.jaci.2018.04.029","title":"Neutropenia among patients with adenosine deaminase deficiency","year":2018,"lang":"en","type":"letter","venue":"Journal of Allergy and Clinical Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario; SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Adenosine deaminase; Purine nucleoside phosphorylase; Adenosine deaminase deficiency; Severe combined immunodeficiency; Enzyme replacement therapy; Immunology; Immunodeficiency; Medicine; Hematopoietic stem cell transplantation; Internal medicine; Transplantation; Biology; Immune system; Purine; Adenosine; Enzyme; Biochemistry; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002628586,0.000372508,0.0004976511,0.0006921771,0.0009048505,0.0007778588,0.0003773371,0.002381344,0.002997604],"category_scores_gemma":[0.003085755,0.0002995027,0.0003222825,0.0006893707,0.0004888354,0.0006695122,0.0003782948,0.00167681,0.0003717528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005178117,"about_ca_system_score_gemma":0.0004483827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001460789,"about_ca_topic_score_gemma":0.001728049,"domain_scores_codex":[0.9996054,0.00008976106,0.00005961485,0.00006090358,0.00005692244,0.000127518],"domain_scores_gemma":[0.9989247,0.0004772447,0.000237123,0.00004999071,0.00006701315,0.0002438902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0005267157,0.0001445175,0.4376067,0.0000610055,0.00005156586,0.5436374,0.0004108868,0.0001604474,0.002154273,0.0006922276,0.00503907,0.009515313],"study_design_scores_gemma":[0.0001125021,0.0002712526,0.2105302,0.0001229803,0.0001304199,0.7807347,0.001100646,0.000706251,0.0004244923,0.001092316,0.004736951,0.00003734184],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9553896,0.003918544,0.000499819,0.01879311,0.0007240149,0.00004870065,0.0002330453,0.00005361723,0.02033949],"genre_scores_gemma":[0.991799,0.0008636828,0.0001919012,0.005111211,0.001232981,0.00001104347,0.00007483506,0.000007399449,0.0007079247],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002997604,"threshold_uncertainty_score":0.010028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016619108772392,"score_gpt":0.2445516661485861,"score_spread":0.2343854750608622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}