{"id":"W2801871966","doi":"10.1212/wnl.90.15_supplement.s36.005","title":"Efficacy of Ozanimod Versus Interferon β-1a by Prior Treatment and Baseline Disability in Two Multicenter, Randomized, Double-Blind, Parallel-Group, Active-Controlled, Double-Dummy Phase 3 Studies in Relapsing Multiple Sclerosis (SUNBEAM and RADIANCE Part B) (S36.005)","year":2018,"lang":"en","type":"article","venue":"Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; McGill University; University of Toronto; NeuroRx Research (Canada)","funders":"","keywords":"Multiple sclerosis; Medicine; Double blind; Interferon beta-1a; Randomized controlled trial; Internal medicine; Pediatrics; Physical therapy; Alternative medicine; Immunology; Interferon beta; Pathology; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002902501,0.001592682,0.003359908,0.0005932619,0.0004524532,0.0007375547,0.00100004,0.001716039,0.004206144],"category_scores_gemma":[0.00262396,0.0008356136,0.001758825,0.0005556041,0.001401819,0.00128368,0.0004826426,0.002391813,0.0005788184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000696097,"about_ca_system_score_gemma":0.001053549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008084807,"about_ca_topic_score_gemma":0.001992843,"domain_scores_codex":[0.9985213,0.0009797781,0.0001315433,0.0001513538,0.00007517469,0.000140805],"domain_scores_gemma":[0.9982148,0.0006220881,0.0004493249,0.000135706,0.00009567291,0.0004823983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9891101,0.002714569,0.0002843657,0.0001658918,0.000259873,0.000006626844,0.00003061117,0.000101656,0.001549154,0.00003005817,0.00009019013,0.005657021],"study_design_scores_gemma":[0.8745283,0.1212451,0.00234036,0.00002051315,0.0003783668,0.00001722642,0.00002679586,0.0003022768,0.0008265874,0.0000758158,0.0002216562,0.00001709423],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941163,0.00267684,0.000413382,0.0002108696,0.0001506776,0.001225139,0.0004098675,0.00006971398,0.0007271871],"genre_scores_gemma":[0.9937021,0.001393056,0.001225467,0.000266459,0.0001708978,0.001610652,0.0006467841,0.00001861045,0.0009660791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004206144,"threshold_uncertainty_score":0.0153501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1485737198198926,"score_gpt":0.4073253572244024,"score_spread":0.2587516374045098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}