{"id":"W2802060268","doi":"10.1158/0008-5472.can-17-2900","title":"HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of British Columbia; BC Cancer Agency","funders":"National Center for Chronic Disease Prevention and Health Promotion; National Institute of Environmental Health Sciences; National Cancer Institute; Cancer Council Victoria; National Human Genome Research Institute; Cancer Council NSW; Medical Research Council; Institut National Du Cancer; Centers for Disease Control and Prevention; National Institutes of Health; Cancer Research UK; Blood Cancer UK; Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail; Cancerfonden; Bundesamt für Strahlenschutz; Leukemia and Lymphoma Research; National Health and Medical Research Council; U.S. Public Health Service; Regione Autonoma della Sardegna; Associazione Italiana per la Ricerca sul Cancro; University of Utah; Fondation de France; Generalitat de Catalunya; Canadian Institutes of Health Research; Bundesministerium für Bildung und Forschung; Leukaemia and Lymphoma Research; Ministerstvo Školství, Mládeže a Tělovýchovy; World Health Organization; University of Southern California; University of Sydney; Stockholms Läns Landsting; Utah Department of Health; Leukemia and Lymphoma Society; Health Research Board; José Carreras Leukämie-Stiftung; U.S. Department of Health and Human Services; Mayo Clinic; University of California, San Francisco; Frederick National Laboratory for Cancer Research; Yale University; Karolinska Institutet; Utah State University; Huntsman Cancer Institute; European Commission; Compagnia di San Paolo; U.S. Department of Veterans Affairs; Michael Smith Health Research BC; Memorial Sloan-Kettering Cancer Center","keywords":"Human leukocyte antigen; Lymphoma; Hodgkin lymphoma; Immunology; Biology; Genetics; Medicine; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007056675,0.00006967014,0.0001348665,0.0001009975,0.0009493671,0.00001124027,0.0002202504,0.0001202527,0.0006247379],"category_scores_gemma":[0.000149878,0.00004697747,0.00003549876,0.0001983355,0.0006051388,0.00004497299,0.0006629937,0.0001749619,0.0002442917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000865923,"about_ca_system_score_gemma":0.0000549399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001292735,"about_ca_topic_score_gemma":0.0004593942,"domain_scores_codex":[0.99908,0.0002933457,0.0001196336,0.0001976493,0.00004719602,0.0002621798],"domain_scores_gemma":[0.9991841,0.0001590637,0.00003746893,0.0002100092,0.0003923354,0.00001700269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001109923,0.00006779464,0.01944812,0.0000115583,0.0001397243,4.851958e-7,0.0007957797,0.000002122734,0.8711435,0.0002335185,0.09856902,0.00847851],"study_design_scores_gemma":[0.0006165923,0.0006406125,0.1005636,0.0000223003,0.000009944742,0.000004364532,0.0003376589,0.000007648096,0.5853145,0.00004221423,0.3123843,0.00005627888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939711,0.00185205,0.00006987432,0.001693867,0.001260926,0.0002362952,0.00001185477,0.00001245596,0.0008915825],"genre_scores_gemma":[0.9944571,0.000273469,0.000002909281,0.0003373585,0.00005413836,0.00002737233,0.000009010534,0.000004216257,0.004834386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2858289,"threshold_uncertainty_score":0.730186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05160377625414884,"score_gpt":0.3517192042981436,"score_spread":0.3001154280439947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}