{"id":"W2802060268","doi":"10.1158/0008-5472.can-17-2900","title":"HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of British Columbia; BC Cancer Agency","funders":"National Center for Chronic Disease Prevention and Health Promotion; National Institute of Environmental Health Sciences; National Cancer Institute; Cancer Council Victoria; National Human Genome Research Institute; Cancer Council NSW; Medical Research Council; Institut National Du Cancer; Centers for Disease Control and Prevention; National Institutes of Health; Cancer Research UK; Blood Cancer UK; Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail; Cancerfonden; Bundesamt für Strahlenschutz; Leukemia and Lymphoma Research; National Health and Medical Research Council; U.S. Public Health Service; Regione Autonoma della Sardegna; Associazione Italiana per la Ricerca sul Cancro; University of Utah; Fondation de France; Generalitat de Catalunya; Canadian Institutes of Health Research; Bundesministerium für Bildung und Forschung; Leukaemia and Lymphoma Research; Ministerstvo Školství, Mládeže a Tělovýchovy; World Health Organization; University of Southern California; University of Sydney; Stockholms Läns Landsting; Utah Department of Health; Leukemia and Lymphoma Society; Health Research Board; José Carreras Leukämie-Stiftung; U.S. Department of Health and Human Services; Mayo Clinic; University of California, San Francisco; Frederick National Laboratory for Cancer Research; Yale University; Karolinska Institutet; Utah State University; Huntsman Cancer Institute; European Commission; Compagnia di San Paolo; U.S. Department of Veterans Affairs; Michael Smith Health Research BC; Memorial Sloan-Kettering Cancer Center","keywords":"Human leukocyte antigen; Lymphoma; Hodgkin lymphoma; Immunology; Biology; Genetics; Medicine; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001364024,0.0002457267,0.0003081406,0.0009820482,0.0003027182,0.0009739237,0.0004383468,0.0004209573,0.004219188],"category_scores_gemma":[0.002536679,0.0002060939,0.0005518934,0.0008290759,0.0004827252,0.0003055667,0.0004921718,0.0005100316,0.0003986611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00012748,"about_ca_system_score_gemma":0.0001047859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009324259,"about_ca_topic_score_gemma":0.000748683,"domain_scores_codex":[0.9990799,0.0004270448,0.00007489986,0.0001968458,0.0001155431,0.0001057062],"domain_scores_gemma":[0.9975411,0.000978626,0.0007684767,0.0003101165,0.0001183509,0.0002834786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002873416,0.00001748469,0.994663,0.000009671529,0.0002240646,0.0001030864,0.00003835864,0.00007526691,0.002029682,0.00007386069,0.0001100907,0.002368037],"study_design_scores_gemma":[0.00002803921,0.00005914738,0.9970729,0.00001189862,0.0001510929,0.0006539262,0.0001714713,0.0007083982,0.0004102949,0.0004151678,0.0003135635,0.000004013362],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979505,0.0007045511,0.000465673,0.00007742631,0.0000105771,0.000005348552,0.0001373832,0.000009026565,0.0006395429],"genre_scores_gemma":[0.9996763,0.00005311346,0.00006599457,0.00001827423,0.00001634439,0.000001681006,0.00007361083,0.000003472127,0.00009130758],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004219188,"threshold_uncertainty_score":0.01411456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05160377625414884,"score_gpt":0.3517192042981436,"score_spread":0.3001154280439947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}