{"id":"W2802181052","doi":"10.3340/jkns.2018.0061","title":"Atypical Teratoid Rhabdoid Tumour : From Tumours to Therapies","year":2018,"lang":"en","type":"review","venue":"Journal of Korean Neurosurgical Society","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Cancer Society","keywords":"SMARCB1; SMARCA4; Medicine; Epigenetics; Cancer research; Epigenetic therapy; Chemotherapy; Chromatin remodeling; Atypical teratoid rhabdoid tumor; Stem cell; Radiation therapy; Bioinformatics; Pathology; Oncology; DNA methylation; Biology; Internal medicine; Gene; Genetics; Medulloblastoma; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004155528,0.0004772929,0.001316746,0.00003699693,0.0001123704,0.0001034934,0.0006553684,0.0004863063,0.00007384807],"category_scores_gemma":[0.0001259633,0.0003302208,0.002360926,0.0001719968,0.0001437894,0.0000056513,0.0002094296,0.0006430435,0.00002545526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006413947,"about_ca_system_score_gemma":0.0003549543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003430152,"about_ca_topic_score_gemma":0.000001377069,"domain_scores_codex":[0.9974247,0.0002439895,0.001038542,0.0004936508,0.0004373569,0.0003618123],"domain_scores_gemma":[0.9982247,0.00009066451,0.000701801,0.0003939774,0.0002206736,0.0003681597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007643535,0.0008511092,0.0001482429,0.002655203,0.00236392,0.0002758117,0.0006481068,0.00006051064,0.01110312,0.00003692873,0.4085335,0.5725592],"study_design_scores_gemma":[0.000384924,0.0005306552,0.00004019493,0.001677182,0.0002789996,0.0002986321,0.00002440546,0.00000990787,0.0003321425,0.00003131967,0.9960295,0.0003621414],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02038737,0.9778184,0.0003948236,0.0001848387,0.0007650589,0.0002069679,0.0001093375,0.00001319566,0.0001200571],"genre_scores_gemma":[0.002540627,0.9907129,0.001443491,0.0006573052,0.004263386,0.000007777912,0.00005906629,0.00008687647,0.0002285263],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.587496,"threshold_uncertainty_score":0.999915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02848556505124351,"score_gpt":0.3135576069513653,"score_spread":0.2850720419001218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}