{"id":"W2802267574","doi":"10.1097/mol.0000000000000519","title":"Predicting cardiovascular disease in familial hypercholesterolemia","year":2018,"lang":"en","type":"review","venue":"Current Opinion in Lipidology","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Familial hypercholesterolemia; Medicine; Disease; Residual risk; Risk stratification; Atherosclerotic cardiovascular disease; Internal medicine; Bioinformatics; Cholesterol; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009412132,0.00109053,0.00201953,0.002430226,0.0001738033,0.0009910521,0.0009615903,0.001100407,0.002378234],"category_scores_gemma":[0.003325268,0.0002603745,0.000762602,0.001685599,0.0003389857,0.0008263577,0.0005264191,0.00130668,0.001071103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003561508,"about_ca_system_score_gemma":0.001183696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001145026,"about_ca_topic_score_gemma":0.001289704,"domain_scores_codex":[0.9995093,0.0001146643,0.0001227222,0.00008290545,0.0001484807,0.00002191007],"domain_scores_gemma":[0.9986327,0.00074955,0.0002522095,0.00001970186,0.0002929839,0.00005281247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001116641,0.00004301661,0.001628757,0.03955271,0.0004881406,0.0002010751,0.00005676439,0.0002836831,0.00036232,0.000905702,0.03199481,0.9243714],"study_design_scores_gemma":[0.000103974,0.0002842445,0.01645026,0.07905579,0.003100829,0.00836507,0.0002648114,0.0006230096,0.000761294,0.003669197,0.8871951,0.0001263604],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009252406,0.9990195,0.00006735674,0.0003358731,0.0002499301,0.000003919548,0.00001914548,0.000004558522,0.0002071535],"genre_scores_gemma":[0.0007281424,0.998492,0.0001386282,0.0001677636,0.0003432029,0.000005233824,0.00003202047,0.000001211478,0.00009175145],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002430226,"threshold_uncertainty_score":0.007955968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1272635995713204,"score_gpt":0.3909030174916906,"score_spread":0.2636394179203702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}