{"id":"W2802339654","doi":"10.1111/imcb.12164","title":"Integration of T‐cell receptor, Notch and cytokine signals programs mouse γδ T‐cell effector differentiation","year":2018,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institutes of Health; Krembil Foundation; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Sunnybrook Research Institute","keywords":"Cell biology; Notch signaling pathway; Biology; Cytokine; T-cell receptor; T cell; Effector; Stromal cell; Receptor; Immunology; Signal transduction; Cancer research; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003587837,0.0004948888,0.0008126911,0.0002922323,0.0003544139,0.00001920237,0.0003446498,0.001329946,0.0006876541],"category_scores_gemma":[0.00004913082,0.0004093569,0.0001260583,0.0002080852,0.0022868,0.0001179939,0.0002936367,0.0006369103,0.0004715023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003183581,"about_ca_system_score_gemma":0.00005315786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002738263,"about_ca_topic_score_gemma":0.00006559549,"domain_scores_codex":[0.9969233,0.0008241563,0.0007231551,0.0007717091,0.00003458951,0.0007231192],"domain_scores_gemma":[0.9983997,0.0003514413,0.0005010982,0.0004816345,0.0002231259,0.00004299113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008029705,0.0006180714,0.002900714,0.00006961077,0.0001809271,0.000001269677,0.0007097444,1.14414e-7,0.9857225,0.0003690676,0.0002719721,0.008353063],"study_design_scores_gemma":[0.003204578,0.003617236,0.001300102,0.00002703814,0.0001160557,0.00003352244,0.000304149,0.000009437393,0.9808345,0.0002789608,0.009877981,0.0003964391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875731,0.008483928,0.0004832759,0.0001291106,0.001229309,0.0005834261,0.00006810765,0.0001244921,0.001325279],"genre_scores_gemma":[0.9931706,0.002032456,0.0002955562,0.0001104525,0.00007944748,0.00007274595,0.0008240952,0.00003703963,0.003377619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009606008,"threshold_uncertainty_score":0.9999666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009014942215847433,"score_gpt":0.2167815987900358,"score_spread":0.2077666565741884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}