{"id":"W2802494678","doi":"10.2337/db18-0123","title":"Placental DNA Methylation Adaptation to Maternal Glycemic Response in Pregnancy","year":2018,"lang":"en","type":"article","venue":"Diabetes","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire de Sherbrooke","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Diabète Québec; American Diabetes Association","keywords":"DNA methylation; Glycemic; Pregnancy; Adaptation (eye); Medicine; Obstetrics; Placenta; Biology; Diabetes mellitus; Endocrinology; Genetics; Fetus; Gene; Neuroscience; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002038802,0.00008935914,0.00007300061,0.00008133778,0.0000371068,0.00002021803,0.00007892148,0.00008476687,0.00001986044],"category_scores_gemma":[0.0001414103,0.0000932791,0.00002656949,0.0001053978,0.00002659352,0.000005080961,0.00004230245,0.00003204364,0.00004127755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002119921,"about_ca_system_score_gemma":0.00002653777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001185065,"about_ca_topic_score_gemma":0.00003504545,"domain_scores_codex":[0.9992507,0.00009604366,0.0001583111,0.0002221073,0.00009293931,0.0001798669],"domain_scores_gemma":[0.9996693,0.00001951548,0.00004595774,0.0001558434,0.00005793883,0.00005148742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006814249,0.00001745383,0.02180204,0.000004431362,0.000006026176,3.633917e-7,0.0001897476,0.0001678415,0.9690619,0.000008605648,0.00001338436,0.008046797],"study_design_scores_gemma":[0.0003868953,0.0008797188,0.07716276,0.00003819619,0.000003440662,1.163887e-7,0.00003372688,0.0006026572,0.91961,0.0001529538,0.001018503,0.0001109975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974843,0.0004928814,0.001412166,0.000072351,0.0001396407,0.0001720374,0.00001044135,0.00000899119,0.0002072515],"genre_scores_gemma":[0.9986529,0.00002321851,0.0009193502,0.00006620319,0.0001314276,0.00002601419,0.00004576945,0.00001483175,0.000120315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05536073,"threshold_uncertainty_score":0.3803811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01263403120496309,"score_gpt":0.2630234188897532,"score_spread":0.2503893876847901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}