{"id":"W2802533205","doi":"10.1128/iai.00208-18","title":"Entamoeba histolytica Alters Ileal Paneth Cell Functions in Intact and Muc2 Mucin Deficiency","year":2018,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Cancer Institute; Government of Canada; National Institutes of Health; Alberta Livestock and Meat Agency; Crohn's and Colitis Canada; Center of Innovation Program; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Paneth cell; Entamoeba histolytica; Mucin 2; Mucin; Biology; Goblet cell; Secretion; Microbiology; Defensin; Mucus; Lysozyme; Ileum; Biochemistry; Gene expression; Small intestine; Epithelium; Antimicrobial; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002067771,0.0007089471,0.0003918872,0.0005182506,0.0001875383,0.0005150219,0.0002420091,0.0007173858,0.002589478],"category_scores_gemma":[0.000244999,0.0003721971,0.0003575967,0.000164777,0.0006053786,0.0003741241,0.0003442138,0.001076278,0.0004003349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003030312,"about_ca_system_score_gemma":0.0001725163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005213683,"about_ca_topic_score_gemma":0.0007305998,"domain_scores_codex":[0.9996483,0.00006903313,0.00004944579,0.00008754974,0.00006479795,0.00008079023],"domain_scores_gemma":[0.9995241,0.00006042143,0.0001407302,0.0000465197,0.00002725777,0.0002010022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002074978,0.00003165703,0.0002035729,0.00002280925,0.000003632756,0.00008488187,0.00001460531,0.00001411232,0.9991912,0.00002118989,0.00001003423,0.0001948178],"study_design_scores_gemma":[0.00008773903,0.001533895,0.02721802,0.00002221684,0.00004280021,0.001532156,0.0002700322,0.0006940918,0.9666578,0.00008220089,0.001844665,0.00001449464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979372,0.000528034,0.0007119834,0.00005397871,0.00002346987,0.00002059383,0.0003122271,0.00006219059,0.0003504976],"genre_scores_gemma":[0.9954571,0.0003679623,0.0009207463,0.00006565571,0.000009565973,0.00004600679,0.0003721282,0.00004263755,0.002718202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002589478,"threshold_uncertainty_score":0.008662641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396005592058169,"score_gpt":0.264779965105281,"score_spread":0.2508199091846993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}