{"id":"W2802718297","doi":"10.1039/c8an00232k","title":"Hg(<scp>ii</scp>) interactions with T-rich regions in oligonucleotides: effects of positional variations on the electrochemical properties","year":2018,"lang":"en","type":"article","venue":"The Analyst","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"University of Toronto Scarborough; Natural Sciences and Engineering Research Council of Canada","keywords":"Electrochemistry; Oligonucleotide; Chemistry; Combinatorial chemistry; DNA; Physical chemistry; Biochemistry; Electrode","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002582971,0.0002956232,0.0002399672,0.00009228841,0.0001274841,0.0003141147,0.0002157358,0.000453558,0.0006786026],"category_scores_gemma":[0.0006266757,0.000183415,0.000136505,0.0001597862,0.0002484268,0.0002137885,0.00016776,0.0003684368,0.0002258078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001468491,"about_ca_system_score_gemma":0.000120886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004808964,"about_ca_topic_score_gemma":0.0009439713,"domain_scores_codex":[0.9996967,0.00009358985,0.00001845574,0.00007211113,0.00007982065,0.00003926642],"domain_scores_gemma":[0.9997031,0.0001114719,0.00007608871,0.00001899187,0.00004905882,0.00004126851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003404605,0.000004753731,0.0001388497,0.0000175419,0.000003627505,0.00002106889,0.00001460836,0.00003677151,0.9990646,0.000009772086,0.000006124664,0.0006483106],"study_design_scores_gemma":[0.000001903306,0.0001484887,0.001081084,0.000002019069,0.000006462906,0.00006387809,0.00001797748,0.0002777502,0.9981735,0.000007703489,0.0002168309,0.000002432384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958094,0.0005583001,0.002922779,0.00004537052,0.00001327288,0.00001100472,0.00004784776,0.00003036435,0.0005616496],"genre_scores_gemma":[0.9931216,0.0003854979,0.005620897,0.00005898584,0.000007592825,0.00001630194,0.00008333844,0.00001640674,0.0006894194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006786026,"threshold_uncertainty_score":0.002270162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007837189557148157,"score_gpt":0.2402046810018501,"score_spread":0.2323674914447019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}