{"id":"W2802757660","doi":"10.1038/s41467-018-02911-y","title":"CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Versus Arthritis; University College London; NIHR Great Ormond Street Hospital Biomedical Research Centre; Nuffield Foundation; Wellcome Trust; Great Ormond Street Institute of Child Health; National Institute for Health and Care Research; Bill and Melinda Gates Foundation","keywords":"Regulatory B cells; CD1D; Cell biology; Antigen presentation; Immune system; Adoptive cell transfer; Natural killer T cell; Biology; Inflammation; Immunology; Downregulation and upregulation; Cytokine; Cytokine storm; Interleukin 10; T cell; Medicine; Disease; Biochemistry; Internal medicine; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002294317,0.0004718742,0.0002234164,0.0003512828,0.000157059,0.0004906544,0.0002580736,0.000225638,0.00115649],"category_scores_gemma":[0.0001703962,0.0001569536,0.0002372622,0.0001538112,0.0004523277,0.0003202665,0.0002927805,0.0008067383,0.000465424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002637045,"about_ca_system_score_gemma":0.0001742226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000108218,"about_ca_topic_score_gemma":0.0001659098,"domain_scores_codex":[0.9997033,0.00007142389,0.00002803051,0.000054989,0.00006023869,0.00008203344],"domain_scores_gemma":[0.9998534,0.00001595035,0.00006197186,0.00002401165,0.00001224578,0.00003235836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003392867,0.00005583065,0.0004163661,0.00006029338,0.000005795132,0.00009524287,0.00002403152,0.0001151323,0.9947102,0.0003425032,0.00006516137,0.003770255],"study_design_scores_gemma":[0.00008527112,0.0004820586,0.002918248,0.00001254557,0.00001975792,0.0004373871,0.0000388394,0.0006129289,0.9905758,0.0001946296,0.004618404,0.000004282628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905758,0.002824207,0.002599951,0.0001833822,0.00005285468,0.00003207792,0.0001616621,0.0001879771,0.003382119],"genre_scores_gemma":[0.9953786,0.0009009229,0.001375449,0.00006117173,0.00002578123,0.00003240458,0.0001341873,0.00002510378,0.002066263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00115649,"threshold_uncertainty_score":0.003868818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01201803801210953,"score_gpt":0.2678502924238316,"score_spread":0.255832254411722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}