{"id":"W2802757660","doi":"10.1038/s41467-018-02911-y","title":"CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":90,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Versus Arthritis; University College London; NIHR Great Ormond Street Hospital Biomedical Research Centre; Nuffield Foundation; Wellcome Trust; Great Ormond Street Institute of Child Health; National Institute for Health and Care Research; Bill and Melinda Gates Foundation","keywords":"Regulatory B cells; CD1D; Cell biology; Antigen presentation; Immune system; Adoptive cell transfer; Natural killer T cell; Biology; Inflammation; Immunology; Downregulation and upregulation; Cytokine; Cytokine storm; Interleukin 10; T cell; Medicine; Disease; Biochemistry; Internal medicine; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002455873,0.0001960026,0.0002728319,0.0001296946,0.0005553003,0.00001525921,0.0009135779,0.0007527747,0.001587299],"category_scores_gemma":[0.0001086147,0.0001836806,0.0001302059,0.0002984235,0.0005677775,0.0002741993,0.0003575061,0.001174344,0.0008502408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007408467,"about_ca_system_score_gemma":0.00006008782,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001615967,"about_ca_topic_score_gemma":0.00005550523,"domain_scores_codex":[0.998428,0.0004224064,0.0005712772,0.0002541838,0.00008345974,0.0002406897],"domain_scores_gemma":[0.9968104,0.0002967094,0.0003737959,0.002047147,0.0004506252,0.00002136474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005799367,0.0002827793,0.00006254583,0.000005405749,0.00009184073,6.1374e-8,0.0004760814,0.00000372239,0.8560213,0.0009732215,0.1417736,0.0002514677],"study_design_scores_gemma":[0.0004910294,0.00007712419,0.001060672,0.00003083309,0.00003692377,0.000004479612,0.0002116166,0.00005076948,0.6536985,0.00005168986,0.3441606,0.0001257981],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6855557,0.1335128,0.004597905,0.01145552,0.04770448,0.003463859,0.001054578,0.001424823,0.1112303],"genre_scores_gemma":[0.9871733,0.001022975,0.0006013745,0.0003690054,0.00003279573,0.00002817851,0.001462736,0.00002716108,0.0092825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3016176,"threshold_uncertainty_score":0.9999277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01201803801210953,"score_gpt":0.2678502924238316,"score_spread":0.255832254411722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}