{"id":"W2802953052","doi":"10.1016/j.cmi.2018.04.012","title":"Efficacy of a Carrageenan gel Against Transmission of Cervical HPV (CATCH): interim analysis of a randomized, double-blind, placebo-controlled, phase 2B trial","year":2018,"lang":"en","type":"article","venue":"Clinical Microbiology and Infection","topic":"Seaweed-derived Bioactive Compounds","field":"Agricultural and Biological Sciences","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Champlain Regional College; McGill University Health Centre; St. Michael's Hospital; Centre Hospitalier de l’Université de Montréal; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health; Roche","keywords":"Placebo; Medicine; Interquartile range; Interim analysis; Confidence interval; Randomized controlled trial; Hazard ratio; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002943101,0.002453628,0.004726657,0.0005302406,0.000718245,0.001518998,0.001141963,0.002984378,0.007917101],"category_scores_gemma":[0.002485791,0.001020555,0.003248552,0.0004141485,0.001515058,0.001822636,0.0004987191,0.004109677,0.001400372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007658022,"about_ca_system_score_gemma":0.001324795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007779377,"about_ca_topic_score_gemma":0.001386554,"domain_scores_codex":[0.999064,0.000390649,0.00006929546,0.0001971271,0.00007076172,0.0002081811],"domain_scores_gemma":[0.9985092,0.0004202275,0.0003552857,0.0001739729,0.0001177591,0.0004234759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9819058,0.004638393,0.0002734342,0.0006016132,0.0009382369,0.00002833957,0.00004756112,0.0001875263,0.002795769,0.0000567609,0.0004106787,0.008115743],"study_design_scores_gemma":[0.9037808,0.0933611,0.001050421,0.00003927007,0.0006469124,0.00002232981,0.00002374284,0.000151186,0.0004271536,0.0000966291,0.0003860226,0.00001443744],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791526,0.008408006,0.001435619,0.000962944,0.0009180062,0.005544896,0.001609884,0.0002471569,0.00172082],"genre_scores_gemma":[0.976151,0.004410157,0.003023412,0.001557024,0.0006753495,0.007543045,0.001898807,0.00006837689,0.004672904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007917101,"threshold_uncertainty_score":0.02648538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06019255689700123,"score_gpt":0.3577360469633386,"score_spread":0.2975434900663374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}