{"id":"W2803074059","doi":"10.1212/wnl.0000000000005660","title":"Typical features of Parkinson disease and diagnostic challenges with microdeletion 22q11.2","year":2018,"lang":"en","type":"article","venue":"Neurology","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Disability Prevention and Rehabilitation","funders":"National Institute of Mental Health; Medical Research Council; Campbell Family Mental Health Research Institute; National Institutes of Health; University of Toronto; Hong Kong Government; Innovation and Technology Commission; Fondation Brain Canada; Parkinson's UK; Canadian Institutes of Health Research; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Sunnybrook Foundation; Dystonia Coalition; National Center for Advancing Translational Sciences; Wellcome Trust","keywords":"Medicine; Deletion syndrome; Pediatrics; Antipsychotic; Levodopa; Dystonia; Internal medicine; Anxiety; Comorbidity; Disease; Age of onset; Psychosis; Mood; Neuroimaging; Parkinson's disease; Psychiatry; Schizophrenia (object-oriented programming)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005079255,0.00007553535,0.00008542634,0.0000315453,0.00003131491,0.000004160837,0.00006629105,0.0000828414,0.00001149607],"category_scores_gemma":[0.0001715845,0.00006231879,0.0000187339,0.00003122896,0.000305427,0.000001468144,0.00008770278,0.00008046172,0.000005847724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001139303,"about_ca_system_score_gemma":0.00002888972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009193708,"about_ca_topic_score_gemma":0.0002356778,"domain_scores_codex":[0.9993544,0.00008786075,0.00006318434,0.0002652777,0.00006880363,0.0001604818],"domain_scores_gemma":[0.9995639,0.0000643142,0.00001924322,0.0001981506,0.00006846949,0.00008594096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02634383,0.0005135251,0.1477303,0.0003487006,0.0001920825,0.0002194754,0.0002081077,0.000006246509,0.7011367,0.001329553,0.002749801,0.1192217],"study_design_scores_gemma":[0.0006329968,0.005602788,0.9206306,0.000006853852,0.00002214233,0.00009910596,0.000003354535,0.00001816145,0.02676101,0.0001405849,0.04597353,0.0001089052],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99473,0.003664183,0.00002325084,0.001076599,0.00003852757,0.0001211031,0.000007407706,0.000005881338,0.0003330694],"genre_scores_gemma":[0.9983854,0.001101539,0.00003715141,0.0002304819,0.000164946,0.00001244319,0.00001018043,0.0000119796,0.00004588208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7729003,"threshold_uncertainty_score":0.2541286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01073461568775587,"score_gpt":0.2562112802299018,"score_spread":0.2454766645421459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}