{"id":"W2803098502","doi":"10.1093/ibd/izy085","title":"Determinants of IBD Heritability: Genes, Bugs, and More","year":2018,"lang":"en","type":"review","venue":"Inflammatory Bowel Diseases","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Canada","keywords":"Disease; Inflammatory bowel disease; Microbiome; Biology; Gut flora; Allele; Genetics; Ulcerative colitis; Genome-wide association study; Immunology; Dysbiosis; Genetic predisposition; Phenotype; Gene; Medicine; Single-nucleotide polymorphism; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000119778,0.0003952601,0.0008380593,0.00006821725,0.00008121318,0.00002076715,0.0002765503,0.0003877174,0.00002579213],"category_scores_gemma":[0.0000704379,0.0003412294,0.0003335066,0.00005257742,0.0003995791,0.000004502683,0.0002603077,0.00008942889,0.00001505966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000214997,"about_ca_system_score_gemma":0.0006503946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009779767,"about_ca_topic_score_gemma":0.00003001534,"domain_scores_codex":[0.998259,0.0001311604,0.0006245231,0.0005675533,0.00011121,0.0003065386],"domain_scores_gemma":[0.9985937,0.00002107824,0.0003642184,0.0006997109,0.00009648375,0.0002247439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001240275,0.0002892707,0.05046241,0.1328838,0.0003665029,0.00009364032,0.0000685934,1.730748e-7,0.0009208479,0.00001808632,0.005673656,0.809099],"study_design_scores_gemma":[0.0001776572,0.0001011275,0.01173274,0.002452425,0.0003823774,0.0000402134,0.00001533131,6.033863e-7,0.00008112146,0.000009088199,0.9846295,0.0003778035],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08097953,0.9177186,9.9959e-7,0.000003249727,0.0001501832,0.0004987387,0.0006085511,0.00001472835,0.00002535301],"genre_scores_gemma":[0.0007240061,0.9982365,0.00005508073,0.00004016062,0.000373944,0.0000589618,0.0002891979,0.0000599875,0.0001621024],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9789559,"threshold_uncertainty_score":0.999904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01854969564557928,"score_gpt":0.3103755973797894,"score_spread":0.2918259017342101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}