{"id":"W2803239181","doi":"10.1093/ndt/gfy104.sp002","title":"SP002CLINICAL OUTCOMES WITH MIGALASTAT IN PATIENTS WITH FABRY DISEASE BASED ON DEGREE OF RENAL IMPAIRMENT: RESULTS FROM PHASE 3 TRIALS","year":2018,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Medicine; Fabry disease; Internal medicine; Kidney disease; Disease; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002288668,0.0008776055,0.001592959,0.0003554873,0.0002819109,0.001053608,0.0005492131,0.001248888,0.003300295],"category_scores_gemma":[0.001544764,0.0002176042,0.002795518,0.0004660153,0.0004574201,0.0005755147,0.0003135716,0.001735732,0.0005014925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008111738,"about_ca_system_score_gemma":0.0008498605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008032091,"about_ca_topic_score_gemma":0.00232986,"domain_scores_codex":[0.9993811,0.0003031955,0.000063525,0.0000763866,0.00009187098,0.00008400171],"domain_scores_gemma":[0.9990977,0.0002468478,0.0002780333,0.00005602035,0.0001240949,0.0001973694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7785898,0.006466751,0.01310414,0.003359902,0.007335535,0.0001392726,0.0001424611,0.002078819,0.01090824,0.0004375084,0.008655421,0.1687821],"study_design_scores_gemma":[0.8022454,0.1422778,0.0401633,0.0004586498,0.003453899,0.0002931984,0.00007315184,0.001335114,0.001805575,0.0007016228,0.007140446,0.00005192682],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9244352,0.05374943,0.001254584,0.002366057,0.0003943765,0.003519135,0.005414252,0.0002376765,0.008629289],"genre_scores_gemma":[0.9780648,0.009614124,0.001467021,0.002381397,0.0002607665,0.002479915,0.004027259,0.00002597938,0.001678579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003300295,"threshold_uncertainty_score":0.0121038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04087493475535003,"score_gpt":0.3390491123198247,"score_spread":0.2981741775644747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}