{"id":"W2803265609","doi":"10.1021/acssynbio.8b00100","title":"Genetic Code Expansion in <i>Rhodobacter sphaeroides</i> to Incorporate Noncanonical Amino Acids into Photosynthetic Reaction Centers","year":2018,"lang":"en","type":"article","venue":"ACS Synthetic Biology","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Division of Molecular and Cellular Biosciences; University of British Columbia; Oregon State University","keywords":"Rhodobacter sphaeroides; Amino acid; Genetic code; Photosynthesis; Photosynthetic reaction centre; Plasmid; Rhodobacter; Biology; Chemistry; Biochemistry; Gene; Mutant","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004437827,0.0005027719,0.0003739606,0.0003384142,0.0002441085,0.0004600745,0.0006279642,0.0004253399,0.0009495906],"category_scores_gemma":[0.0006224043,0.0002655752,0.0005124745,0.0002998055,0.0003074586,0.0002288948,0.0006092428,0.0009532942,0.0009741556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006712186,"about_ca_system_score_gemma":0.0008147769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002568346,"about_ca_topic_score_gemma":0.003220452,"domain_scores_codex":[0.9993823,0.0001135912,0.0001052546,0.0001160744,0.0001830259,0.00009991009],"domain_scores_gemma":[0.999493,0.00007969077,0.000168934,0.0001214115,0.00006691828,0.00006990325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008713534,0.00007473124,0.000250847,0.00004050713,0.000008866022,0.0002029897,0.00006128913,0.0004519509,0.9941533,0.0004977806,0.0001175342,0.004053018],"study_design_scores_gemma":[0.0000384233,0.000251694,0.001694383,0.00002208125,0.00002218855,0.0004021817,0.00006733281,0.003896154,0.9848992,0.0001247915,0.008557236,0.000024341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9452261,0.0004018055,0.04661351,0.0004682515,0.0001748093,0.0007001283,0.001120539,0.001420664,0.003874119],"genre_scores_gemma":[0.932621,0.0004216952,0.05882917,0.000143555,0.00001766764,0.0002767571,0.001646878,0.0006041646,0.005439102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002568346,"threshold_uncertainty_score":0.005106807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01090728262614927,"score_gpt":0.2609377223987567,"score_spread":0.2500304397726074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}