{"id":"W2803286407","doi":"10.1080/02648725.2018.1471643","title":"Vaccinia-based vaccines to biothreat and emerging viruses","year":2018,"lang":"en","type":"review","venue":"Biotechnology and Genetic Engineering Reviews","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Defence Research and Development Canada","funders":"","keywords":"Vaccinia; Smallpox; Virology; Smallpox vaccine; Vaccination; Oncolytic virus; Modified vaccinia Ankara; Viral vector; Attenuated vaccine; Biology; Medicine; Virus; Immunology; Virulence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000369495,0.0006721773,0.001331383,0.0004641907,0.0001043713,0.00003887186,0.0004683365,0.001029553,0.00002228897],"category_scores_gemma":[0.0002775668,0.0005616792,0.0002254051,0.0004306298,0.00009396205,0.000002580416,0.0003595126,0.0003265559,0.00006305394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002175781,"about_ca_system_score_gemma":0.0000880384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003053167,"about_ca_topic_score_gemma":0.00002354011,"domain_scores_codex":[0.9976332,0.0001115383,0.0006395336,0.0009914582,0.0000976319,0.0005267049],"domain_scores_gemma":[0.9985968,0.00003811684,0.0001575362,0.0009742418,0.00003940309,0.000193848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004863715,0.00001973547,0.00001096091,0.005913503,0.0001362941,0.00000790889,0.000005339286,0.000007146372,0.008205483,0.000008293445,0.001049212,0.9845875],"study_design_scores_gemma":[0.00018854,0.001469578,0.000007763014,0.002441336,0.0001738493,0.00007900251,9.772842e-7,0.00002584366,0.007285405,0.000002585142,0.9877558,0.0005693414],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003767147,0.9937045,0.0008976465,0.0001455663,0.0001484459,0.001232004,0.00002380041,0.00007524348,0.000005646648],"genre_scores_gemma":[0.00005308309,0.994839,0.004103418,0.0001828193,0.000316045,0.000297186,0.00003298479,0.0001105642,0.00006487336],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9867066,"threshold_uncertainty_score":0.9996834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03228112512438948,"score_gpt":0.3360254019159994,"score_spread":0.30374427679161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}