{"id":"W2803286407","doi":"10.1080/02648725.2018.1471643","title":"Vaccinia-based vaccines to biothreat and emerging viruses","year":2018,"lang":"en","type":"review","venue":"Biotechnology and Genetic Engineering Reviews","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Defence Research and Development Canada","funders":"","keywords":"Vaccinia; Smallpox; Virology; Smallpox vaccine; Vaccination; Oncolytic virus; Modified vaccinia Ankara; Viral vector; Attenuated vaccine; Biology; Medicine; Virus; Immunology; Virulence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006975178,0.000998911,0.0009344723,0.002070542,0.0003428843,0.0008062737,0.0008957863,0.001177642,0.003496682],"category_scores_gemma":[0.0006617015,0.0003440623,0.000512495,0.001571208,0.0007469975,0.00155618,0.0008340711,0.002548443,0.003362967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007450588,"about_ca_system_score_gemma":0.0008024727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006333967,"about_ca_topic_score_gemma":0.001024059,"domain_scores_codex":[0.9997481,0.00004369199,0.00002170006,0.00004405912,0.0001096202,0.00003282475],"domain_scores_gemma":[0.9997939,0.00008866809,0.00003022781,0.00001231977,0.00005000049,0.00002478555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006337289,0.0001456518,0.0001207935,0.01474958,0.00007387036,0.0002310512,0.0001511926,0.0006031375,0.01216162,0.01424636,0.04638356,0.9110698],"study_design_scores_gemma":[0.000007415581,0.00004871912,0.0001415325,0.0008882559,0.00001882612,0.0003974286,0.00001627274,0.00003800522,0.001002353,0.001269305,0.9961648,0.000007025178],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002099205,0.9957737,0.0005697235,0.0002879336,0.0005128651,0.00001491544,0.0000181078,0.00002427769,0.002588505],"genre_scores_gemma":[0.001231939,0.9953368,0.0005257573,0.0002983421,0.0002117436,0.00001872929,0.00003877562,0.000004750872,0.002333222],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003496682,"threshold_uncertainty_score":0.01169753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03228112512438948,"score_gpt":0.3360254019159994,"score_spread":0.30374427679161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}