{"id":"W2803302018","doi":"10.1097/mot.0000000000000540","title":"Human leukocyte antigen mismatch and precision medicine in transplantation","year":2018,"lang":"en","type":"review","venue":"Current Opinion in Organ Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Shared Health","funders":"Canadian Institutes of Health Research","keywords":"Immunosuppression; Human leukocyte antigen; Context (archaeology); Precision medicine; Medicine; Intensive care medicine; Immunology; Kidney transplantation; Transplantation; Personalized medicine; Organ transplantation; Bioinformatics; Antigen; Internal medicine; Biology; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001783215,0.0006880062,0.001576138,0.002401581,0.000343742,0.001530489,0.0009644373,0.001707225,0.004479062],"category_scores_gemma":[0.00497976,0.000228724,0.0009076885,0.002432453,0.0008748666,0.001690655,0.001017848,0.002276329,0.001045806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009393253,"about_ca_system_score_gemma":0.002731246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001368352,"about_ca_topic_score_gemma":0.001666555,"domain_scores_codex":[0.9991478,0.0002708735,0.0001616904,0.000100765,0.0002738757,0.00004494959],"domain_scores_gemma":[0.9964377,0.00260512,0.0003622927,0.00006390264,0.000442807,0.00008825472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006748128,0.00003927277,0.0003714811,0.05668086,0.0003081848,0.0001872224,0.0001170385,0.0004478387,0.0003309643,0.009734876,0.04619606,0.8855187],"study_design_scores_gemma":[0.00001739407,0.00006054713,0.001001794,0.03132037,0.0003233493,0.00151343,0.0001225441,0.0001319713,0.000220499,0.006362224,0.9588975,0.00002834787],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003647645,0.9984019,0.0001068628,0.0007228396,0.0002822831,0.000003410776,0.00001151184,0.000003791824,0.0004309194],"genre_scores_gemma":[0.0005262554,0.998368,0.0001419048,0.0004343257,0.0003719408,0.000005406402,0.00001515962,0.000001198346,0.0001359083],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004479062,"threshold_uncertainty_score":0.01498389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1218512878507627,"score_gpt":0.4362431982973085,"score_spread":0.3143919104465458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}