{"id":"W2803417520","doi":"10.1111/imm.12950","title":"Segmented filamentous bacteria‐induced immune responses: a balancing act between host protection and autoimmunity","year":2018,"lang":"en","type":"review","venue":"Immunology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Canadian Institutes of Health Research; Alberta Innovates; Canadian Association of Gastroenterology","keywords":"Segmented filamentous bacteria; Biology; Immune system; Autoimmunity; Immunity; Immunology; Microbiology; Acquired immune system; Innate immune system; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002897271,0.0006567098,0.0008356523,0.001432503,0.000294097,0.0009492799,0.0005569864,0.0009844712,0.003328263],"category_scores_gemma":[0.0004184515,0.000170264,0.0002516125,0.001462425,0.0003638026,0.001147474,0.0006962273,0.00134605,0.002115534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005080962,"about_ca_system_score_gemma":0.0009170242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004397465,"about_ca_topic_score_gemma":0.0007667036,"domain_scores_codex":[0.9998968,0.00001509054,0.00001380995,0.00001832791,0.00004053215,0.00001548256],"domain_scores_gemma":[0.9998466,0.0000529567,0.00002620162,0.00000600762,0.00004250717,0.00002564788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006837118,0.00005281416,0.0002101533,0.01477267,0.00005437257,0.0002870641,0.0000927978,0.0002251451,0.004662988,0.007028722,0.03223543,0.9403093],"study_design_scores_gemma":[0.00000626625,0.00004872778,0.0005404801,0.001949946,0.000038546,0.001170034,0.00005593683,0.00003803492,0.0006060174,0.002104837,0.9934308,0.00001039868],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002219734,0.9970207,0.0002336065,0.0004105899,0.0003676618,0.000004212045,0.00002552661,0.0000146547,0.001701121],"genre_scores_gemma":[0.000992984,0.9974641,0.0001997182,0.0001902645,0.0001965068,0.000005693161,0.00003187895,0.000002109083,0.0009166879],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003328263,"threshold_uncertainty_score":0.01113415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04370058300971092,"score_gpt":0.3276361294341869,"score_spread":0.283935546424476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}