{"id":"W2803625437","doi":"10.1016/j.jaad.2018.05.032","title":"Maintenance of skin clearance with ixekizumab treatment of psoriasis: Three-year results from the UNCOVER-3 study","year":2018,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Innovaderm (Canada)","funders":"","keywords":"Ixekizumab; Medicine; Psoriasis; Dermatology; Plaque psoriasis; Secukinumab; Psoriatic arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001879942,0.0002290913,0.001067197,0.00009286203,0.0001037882,0.000002865367,0.0007407058,0.0001213008,0.0000224102],"category_scores_gemma":[0.00009607752,0.0001084815,0.0002786016,0.000349061,0.001723629,0.00006443569,0.00007352902,0.0002252143,0.0000127805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004748542,"about_ca_system_score_gemma":0.0001315416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004980344,"about_ca_topic_score_gemma":0.0001176653,"domain_scores_codex":[0.9977832,0.0006568671,0.0009506982,0.0002094318,0.000127678,0.0002721474],"domain_scores_gemma":[0.9958435,0.0006208861,0.00297561,0.0003785502,0.0001572518,0.00002414905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1129852,0.006444005,0.640187,0.0000431593,0.01987427,0.00008662637,0.0208134,0.0001103945,0.0565479,0.0007148223,0.0109961,0.1311971],"study_design_scores_gemma":[0.0140139,0.005890545,0.800362,0.0001709506,0.001272842,0.0008486259,0.004370655,0.000002953815,0.1662641,0.0003426693,0.006273649,0.0001870966],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948281,0.001325951,0.00002547877,0.002946133,0.000300551,0.0002877358,0.0001581376,0.000005366622,0.0001225327],"genre_scores_gemma":[0.9989626,0.0004558702,0.000271899,0.0001208435,0.0000903074,0.000005370669,0.000002116219,0.00001577637,0.00007520611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.160175,"threshold_uncertainty_score":0.6350784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01763828156888338,"score_gpt":0.2649024284487477,"score_spread":0.2472641468798644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}