{"id":"W2803644870","doi":"10.1186/s13053-018-0089-x","title":"Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East Poland","year":2018,"lang":"en","type":"article","venue":"Hereditary Cancer in Clinical Practice","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital","funders":"Breast Cancer Campaign","keywords":"Founder effect; Ovarian cancer; Medicine; Mutation; Cancer; Genetics; Internal medicine; Oncology; Biology; Gene; Haplotype; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002202344,0.0001751651,0.0003524384,0.001058555,0.0003777245,0.0003798646,0.000164057,0.0003007064,0.001189835],"category_scores_gemma":[0.001168377,0.0003482862,0.0001953148,0.0008751249,0.0004093366,0.0002639563,0.0004363177,0.0002391178,0.0001470046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002323067,"about_ca_system_score_gemma":0.0002478952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003427432,"about_ca_topic_score_gemma":0.00348965,"domain_scores_codex":[0.9997455,0.00003186942,0.00003941372,0.000089818,0.00005067797,0.00004266968],"domain_scores_gemma":[0.9995559,0.0000687644,0.0002062539,0.00003841789,0.00004046971,0.00009011599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009097974,0.00001901752,0.9962608,0.00001200651,0.00002315917,0.0007025289,0.0002181026,0.00002045496,0.001071549,0.00001516741,0.00006248963,0.001503738],"study_design_scores_gemma":[0.00001747546,0.00004980009,0.9964205,0.00000624908,0.00002414939,0.002680682,0.0003089188,0.00005989516,0.0001625567,0.00002681312,0.0002388265,0.000004010548],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996867,0.0001050242,0.00001656953,0.00001121349,9.541404e-7,0.000003756055,0.00003664603,0.000001237273,0.0001378815],"genre_scores_gemma":[0.9996561,0.0001286869,0.00003354859,0.00001697147,0.000002510827,0.000004379524,0.00007914508,0.000001383269,0.00007720749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003427432,"threshold_uncertainty_score":0.006815016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04297381109403484,"score_gpt":0.3886820962755594,"score_spread":0.3457082851815246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}