{"id":"W2803851177","doi":"10.1007/s10534-018-0105-7","title":"Are lactoferrin receptors in Gram-negative bacteria viable vaccine targets?","year":2018,"lang":"en","type":"article","venue":"BioMetals","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Lactoferrin; Neisseria meningitidis; Transferrin; Bacterial outer membrane; Microbiology; Biology; Neisseria; Transferrin receptor; Moraxella catarrhalis; Receptor; Bacteria; Streptococcus pneumoniae; Antibiotics; Biochemistry; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008501452,0.0002672371,0.0004034204,0.0001829541,0.0001943,0.00118579,0.0003603634,0.001402823,0.003849263],"category_scores_gemma":[0.0007900176,0.0001372591,0.0001455626,0.0001583127,0.0009328582,0.003062093,0.0004174861,0.0008589326,0.001174482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003782717,"about_ca_system_score_gemma":0.0003548505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002097819,"about_ca_topic_score_gemma":0.0002035535,"domain_scores_codex":[0.9997832,0.00005088672,0.000007834514,0.00002676085,0.0000552131,0.00007615486],"domain_scores_gemma":[0.9997727,0.00008717419,0.00004781359,0.00001797019,0.00004017318,0.0000342144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001434594,0.0001490713,0.002323774,0.001102147,0.00007643677,0.0006765103,0.0003764399,0.001125408,0.6673487,0.1058457,0.01232728,0.2072139],"study_design_scores_gemma":[0.0001267173,0.001922141,0.006966693,0.0005473642,0.0001244057,0.003269221,0.002306159,0.002809256,0.5183526,0.09139657,0.372102,0.00007702642],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.438216,0.4207084,0.04060298,0.07026642,0.002685095,0.00005212407,0.0004684583,0.0003120934,0.02668839],"genre_scores_gemma":[0.8974402,0.08044694,0.004746423,0.004349529,0.0008802023,0.0000482041,0.0001992091,0.00004000748,0.0118494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003849263,"threshold_uncertainty_score":0.01287711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02203418024458076,"score_gpt":0.2700934211247173,"score_spread":0.2480592408801365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}