{"id":"W2803986511","doi":"10.3390/biom8020029","title":"Critical Assessment of Methods to Quantify Biofilm Growth and Evaluate Antibiofilm Activity of Host Defence Peptides","year":2018,"lang":"en","type":"article","venue":"Biomolecules","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":293,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Killam Trusts; Cystic Fibrosis Canada","keywords":"Biofilm; Microbiology; Bacteria; Pseudomonas aeruginosa; Crystal violet; Staphylococcus aureus; Biology; Antibiotics; Staining; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004652807,0.0001842944,0.0002824308,0.00008225255,0.00007264545,0.00002714443,0.0001439499,0.0001565286,0.00000943253],"category_scores_gemma":[0.0004476659,0.0001651488,0.00008584778,0.0001695987,0.0007245322,0.000008377951,0.0002333457,0.0000512347,0.000001614969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005608819,"about_ca_system_score_gemma":0.00008365735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000144881,"about_ca_topic_score_gemma":0.00001839379,"domain_scores_codex":[0.9986797,0.0002272694,0.0002719165,0.0004230503,0.0001337374,0.0002643313],"domain_scores_gemma":[0.9990925,0.00005728971,0.0001144486,0.0003206337,0.0002948546,0.00012024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001040057,0.00007743222,0.002816346,0.0000697628,0.00003914491,0.000001016083,0.00002357562,7.537153e-8,0.9916364,0.001403267,0.00004994069,0.003779016],"study_design_scores_gemma":[0.0001985493,0.0009997434,0.05793261,0.00004745988,0.00003137168,0.00001135714,0.00003809057,0.00006810752,0.9402052,0.00002346158,0.0002592105,0.0001848691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875359,0.0001879947,0.01104659,0.0002851765,0.0001881976,0.0001508584,0.0000684305,0.000008852923,0.0005280123],"genre_scores_gemma":[0.8674195,0.00007200193,0.1322979,0.00008140939,0.00009308939,0.000001961224,0.000009780778,0.00001643324,0.000007852947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1212513,"threshold_uncertainty_score":0.6734571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03264780302021356,"score_gpt":0.3949472536890264,"score_spread":0.3622994506688128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}