{"id":"W2803987989","doi":"10.1016/j.peptides.2018.05.007","title":"Bifunctional ligands of the bradykinin B 2 and B 1 receptors: An exercise in peptide hormone plasticity","year":2018,"lang":"en","type":"review","venue":"Peptides","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôpital Saint-François d'Assise","funders":"Canadian Institutes of Health Research","keywords":"Kinin; Bradykinin; Chemistry; Agonist; Bradykinin receptor; Receptor; Kallikrein; Biochemistry; Peptide; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003614916,0.0004468356,0.00157237,0.0002846958,0.000112383,0.00003241027,0.0002175078,0.000338019,0.0001393176],"category_scores_gemma":[0.0002954328,0.0002963833,0.0003836197,0.0005338862,0.0004137203,0.0001506458,0.000134965,0.0003427452,0.00002578163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008524151,"about_ca_system_score_gemma":0.0003738592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001886476,"about_ca_topic_score_gemma":0.0001009517,"domain_scores_codex":[0.9977785,0.00007893731,0.0008818312,0.0005339108,0.0004062576,0.00032051],"domain_scores_gemma":[0.9984939,0.0003096433,0.000456392,0.000435154,0.0001250692,0.000179809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004483568,0.0009649986,0.01907059,0.02136582,0.0004798616,0.00002204179,0.001800449,0.000004809333,0.0000630923,0.0005247408,0.02678696,0.9284683],"study_design_scores_gemma":[0.001377868,0.0005981928,0.04922348,0.04742576,0.00175329,0.000135777,0.0001203591,0.00009324068,0.0001295034,0.0003352697,0.8981295,0.0006777693],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02602658,0.9722288,0.000004870793,0.00004400299,0.000404337,0.0007693119,0.00005781516,0.00004839562,0.0004158877],"genre_scores_gemma":[0.007205344,0.9897439,0.0001892629,0.00003578461,0.0006805248,0.0000645671,0.0001256861,0.00006996297,0.001884921],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9277905,"threshold_uncertainty_score":0.9999489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04338932673271916,"score_gpt":0.3105243273860131,"score_spread":0.2671350006532939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}