{"id":"W2804165635","doi":"10.1200/edbk_208509","title":"Cardiac Toxicities in the Era of Precision Medicine: Underlying Risk Factors, Targeted Therapies, and Cardiac Biomarkers","year":2018,"lang":"en","type":"review","venue":"American Society of Clinical Oncology Educational Book","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Medicine; Disease; Myocarditis; Internal medicine; Intensive care medicine; Hyperlipidemia; Cardiology; Cardiotoxicity; Cancer; Heart failure; Cardiomyopathy; Oncology; Chemotherapy; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.003637698,0.000371438,0.003977434,0.00008886295,0.0001033168,0.000006093444,0.0002555301,0.000599322,0.0001118004],"category_scores_gemma":[0.001278956,0.0002379545,0.001769735,0.0004811891,0.004293369,0.00007058134,0.00004896959,0.001146193,0.000002137864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002790875,"about_ca_system_score_gemma":0.003101081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006286409,"about_ca_topic_score_gemma":0.000004624418,"domain_scores_codex":[0.9949746,0.001785164,0.001931118,0.0005239598,0.0005372998,0.0002478227],"domain_scores_gemma":[0.981684,0.01524449,0.002171266,0.0004867337,0.0002759958,0.0001375501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007868786,0.000335092,0.005569873,0.001319228,0.002846314,2.747182e-7,0.004879772,1.232672e-7,0.00005100709,0.000109988,0.02772882,0.9570808],"study_design_scores_gemma":[0.0006374077,0.001585615,0.03996849,0.002880935,0.001796473,0.000004509441,0.008306092,0.000002129546,0.00001603195,0.000281956,0.9442942,0.0002261524],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03076795,0.9614855,0.00001781541,0.004513341,0.0006664989,0.001408551,0.0001245266,0.0000130557,0.001002758],"genre_scores_gemma":[0.005319171,0.9901282,0.001861674,0.001014716,0.0009003991,0.00009521515,0.0003208173,0.00003653894,0.0003232821],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9568547,"threshold_uncertainty_score":0.9984164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.124368947853797,"score_gpt":0.466152154709184,"score_spread":0.341783206855387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}