{"id":"W2804210907","doi":"10.1016/j.jmb.2018.05.015","title":"Regulation of Shigella Effector Kinase OspG through Modulation of Its Dynamic Properties","year":2018,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Western University; University of Calgary; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Effector; Shigella; Shigella flexneri; Kinase; Modulation (music); Cell biology; Biology; Chemistry; Computational biology; Biochemistry; Physics; Bacteria; Genetics; Salmonella; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008368025,0.0002157465,0.0001160596,0.0001015309,0.0001096847,0.0003383244,0.0001514976,0.0001295741,0.001176499],"category_scores_gemma":[0.0001370023,0.00009305219,0.0001349948,0.00007133237,0.0002160209,0.0002704799,0.0002323047,0.0002705782,0.0003018565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002772305,"about_ca_system_score_gemma":0.00009874549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001686163,"about_ca_topic_score_gemma":0.0001657479,"domain_scores_codex":[0.9999533,0.000006964157,0.000002666137,0.00001062191,0.000009719251,0.00001669423],"domain_scores_gemma":[0.9999346,0.00001328371,0.00001676789,0.0000075465,0.000009052338,0.00001871991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001443272,0.00001353122,0.0002468087,0.00001405971,0.000002564295,0.00003133392,0.00001097706,0.00007683691,0.9981269,0.0003219922,0.00003439763,0.000976095],"study_design_scores_gemma":[0.00002022944,0.00008269191,0.008047299,0.00000424272,0.000007290423,0.0001245212,0.00004747999,0.003898805,0.9861239,0.0003142888,0.001322159,0.000007093654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971512,0.0004273911,0.001218511,0.00008518192,0.00001732422,0.000004027961,0.00006763889,0.00003155683,0.0009972199],"genre_scores_gemma":[0.9991187,0.0001109113,0.0001992064,0.00001195461,0.000003126132,0.000003632222,0.00006440455,0.000006644729,0.0004814282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001176499,"threshold_uncertainty_score":0.003935814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0151660470839335,"score_gpt":0.3071168736160735,"score_spread":0.2919508265321401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}