{"id":"W2804360725","doi":"10.1097/rhu.0000000000000786","title":"Tofacitinib 5 mg Twice Daily in Patients with Rheumatoid Arthritis and Inadequate Response to Disease-Modifying Antirheumatic Drugs","year":2018,"lang":"en","type":"review","venue":"JCR Journal of Clinical Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Pfizer","keywords":"Tofacitinib; Medicine; Janus kinase inhibitor; Rheumatoid arthritis; Placebo; Adalimumab; Adverse effect; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005385134,0.0002954384,0.002144,0.001513385,0.0003010566,0.0006176511,0.000349677,0.0007264463,0.002294507],"category_scores_gemma":[0.00609921,0.0001865857,0.001738621,0.001801083,0.0002438633,0.0006389159,0.0002127881,0.0004812193,0.0002220767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005198813,"about_ca_system_score_gemma":0.0007960435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008924128,"about_ca_topic_score_gemma":0.002901559,"domain_scores_codex":[0.9973494,0.001131243,0.0008452765,0.0002048663,0.0003877516,0.00008141492],"domain_scores_gemma":[0.9918157,0.004130104,0.003404384,0.0001037071,0.0003819884,0.0001639787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.04748748,0.0005125318,0.2839102,0.1416167,0.02132324,0.00303155,0.0005496574,0.0006243293,0.005104487,0.000516663,0.0122636,0.4830594],"study_design_scores_gemma":[0.03349544,0.02363647,0.6818568,0.07462879,0.0564482,0.02029428,0.001020207,0.001231734,0.003176253,0.001920662,0.1021193,0.0001719223],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1189993,0.8736187,0.0002780402,0.001410265,0.0002434936,0.0002290882,0.0009999656,0.00001725093,0.004203922],"genre_scores_gemma":[0.8400705,0.1530751,0.001245151,0.003020146,0.0007000265,0.0002105074,0.001257485,0.000007629108,0.0004135369],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005385134,"threshold_uncertainty_score":0.02847964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04898100704138098,"score_gpt":0.3946032902520369,"score_spread":0.3456222832106559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}