{"id":"W2804485307","doi":"10.1111/ejn.13941","title":"Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum","year":2018,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University; Université de Montréal","funders":"National Institute of Biomedical Imaging and Bioengineering; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; National Institute on Drug Abuse; Fonds de Recherche du Québec-Société et Culture; Canada Foundation for Innovation; Fonds de Recherche du Québec - Santé; Michael J. Fox Foundation for Parkinson's Research","keywords":"Microdialysis; Dopamine; Striatum; Dopaminergic; Anesthesia; Pharmacology; Drug; Chemistry; Addiction; Psychology; Medicine; Internal medicine; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001708995,0.0002483679,0.0002149027,0.0001363221,0.00005237364,0.0003251335,0.0001497771,0.0001828977,0.0005989979],"category_scores_gemma":[0.0003330206,0.0001638672,0.0002271713,0.0001066866,0.0001902277,0.0002140828,0.0001262518,0.0003607635,0.0001026887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002911079,"about_ca_system_score_gemma":0.0002531139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000588106,"about_ca_topic_score_gemma":0.001053803,"domain_scores_codex":[0.9998368,0.0000277069,0.00001286789,0.00005253671,0.00003867295,0.00003141772],"domain_scores_gemma":[0.9997702,0.00005204755,0.0001095494,0.00001992178,0.00001990484,0.00002838182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009739098,0.0001066181,0.00405345,0.00003080936,0.00002692601,0.00003106175,0.00001587329,0.0004295035,0.9870502,0.00005809744,0.00003420917,0.007189216],"study_design_scores_gemma":[0.00005431923,0.003905984,0.06699725,0.000008359489,0.00007436676,0.0001696151,0.00002482082,0.008949969,0.9191114,0.00008211546,0.0006018152,0.00002001386],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968938,0.0002642192,0.002267182,0.00003180625,0.000007808564,0.00002869654,0.0001624981,0.00003384367,0.0003102048],"genre_scores_gemma":[0.9951221,0.0004824309,0.003609261,0.00004026086,0.000008198183,0.00005759412,0.0001956177,0.00001729314,0.000467327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005989979,"threshold_uncertainty_score":0.00211215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03373301384520713,"score_gpt":0.2790075248116276,"score_spread":0.2452745109664205,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}