{"id":"W2804492207","doi":"10.1016/j.cllc.2018.05.002","title":"Rationale and Protocol for a Canadian Multicenter Phase II Randomized Trial Assessing Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non–small-cell Lung Cancer (NCT02788461)","year":2018,"lang":"en","type":"article","venue":"Clinical Lung Cancer","topic":"Lung Cancer Diagnosis and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Cancer Care Ontario; Princess Margaret Cancer Centre; BC Cancer Agency; University of Toronto","funders":"","keywords":"Medicine; Lung cancer; Randomized controlled trial; Radiation therapy; Oncology; Population; Internal medicine; Nuclear medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04694621,0.005667594,0.006222734,0.003376242,0.008461175,0.005430803,0.004714085,0.007794813,0.07016598],"category_scores_gemma":[0.02977627,0.004096915,0.008329777,0.003974795,0.006847104,0.002020508,0.002557221,0.01418892,0.016385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.02409541,"about_ca_system_score_gemma":0.07720841,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03982525,"about_ca_topic_score_gemma":0.1111601,"domain_scores_codex":[0.9713359,0.01563369,0.003222336,0.002716672,0.004060441,0.003030914],"domain_scores_gemma":[0.9841632,0.003400525,0.00282363,0.001824132,0.004100947,0.003687547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.528163,0.009426024,0.002989919,0.02325349,0.004046072,0.0004740408,0.0007829797,0.005731229,0.005829995,0.03777576,0.2308522,0.1506753],"study_design_scores_gemma":[0.6654932,0.01465805,0.006787891,0.007676793,0.002683463,0.0002094392,0.0001963117,0.001867156,0.001481183,0.01191126,0.2867478,0.0002873953],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.001439464,0.001113893,0.003019045,0.002198508,0.0009891329,0.9770749,0.007833306,0.0001431155,0.006188623],"genre_scores_gemma":[0.003834056,0.0004172575,0.01367188,0.00321922,0.0002535437,0.974361,0.002071186,0.00002645577,0.002145461],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.9601747,"threshold_uncertainty_score":0.2482783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03836284371604642,"score_gpt":0.4455259397304963,"score_spread":0.4071630960144498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}