{"id":"W2804518990","doi":"10.1371/journal.pone.0197583","title":"Efficacy and safety of direct oral anticoagulants approved for cardiovascular indications: Systematic review and meta-analysis","year":2018,"lang":"en","type":"review","venue":"PLoS ONE","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; National Institutes of Health; National Science Foundation","keywords":"Medicine; Stroke (engine); Internal medicine; Odds ratio; Atrial fibrillation; Randomized controlled trial; Rivaroxaban; Confidence interval; Meta-analysis; Edoxaban; Gastrointestinal bleeding; Apixaban; Warfarin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001546459,0.0003096921,0.01447626,0.0003350551,0.00005703414,0.00001798661,0.00009880201,0.000125293,0.00003649988],"category_scores_gemma":[0.001336929,0.0001929214,0.003503376,0.000616551,0.00006940464,0.00004029416,0.0000717193,0.00006844181,0.000006842209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000216329,"about_ca_system_score_gemma":0.00003609345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004850106,"about_ca_topic_score_gemma":0.000001111373,"domain_scores_codex":[0.9975282,0.0003273324,0.001186235,0.0004126386,0.0004090699,0.0001365282],"domain_scores_gemma":[0.9976036,0.0005636393,0.000780621,0.0007989003,0.0001727063,0.00008051254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.000005403159,0.00002212438,0.0000102121,0.5567433,0.4428103,2.708656e-7,0.000005377943,2.138128e-8,3.95e-8,0.00002087161,0.00001599499,0.0003661789],"study_design_scores_gemma":[0.0003719534,0.00005149456,0.00001781352,0.04471962,0.9409239,0.000001645188,0.000002017481,0.000006834356,5.765411e-7,0.000003752673,0.01374474,0.000155679],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000001901327,0.9886109,0.0001934374,0.0001298757,0.000006524822,0.01086608,0.00008907179,0.00002631131,0.00007592043],"genre_scores_gemma":[0.00002466011,0.9960195,0.002422992,0.00004570057,0.00006651906,0.0001879916,0.0002959873,0.00003093292,0.0009057179],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5120236,"threshold_uncertainty_score":0.9895683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3804335335244292,"score_gpt":0.3866749991366601,"score_spread":0.006241465612230879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}