{"id":"W2804736643","doi":"10.1016/j.virol.2018.05.011","title":"An important role of SREBP-1 in HBV and HCV co-replication inhibition by PTEN","year":2018,"lang":"en","type":"article","venue":"Virology","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Saskatchewan Health Research Foundation; Public Health Agency; Public Health Agency of Canada; University of Saskatchewan","keywords":"PTEN; Tensin; HBx; Gene knockdown; Biology; Cancer research; Virology; Hepatitis B virus; Cell biology; PI3K/AKT/mTOR pathway; Virus; Apoptosis; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003585874,0.0003696342,0.0003318444,0.0003808748,0.0002768715,0.0005238625,0.0003139216,0.0002794924,0.002466521],"category_scores_gemma":[0.0003564957,0.0001774743,0.0004265458,0.0001863489,0.0004232639,0.0005277897,0.0006159989,0.0006742866,0.0003625109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002374618,"about_ca_system_score_gemma":0.0004195387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004020228,"about_ca_topic_score_gemma":0.000448046,"domain_scores_codex":[0.9997303,0.00006162802,0.00002281696,0.00003417942,0.00006849853,0.00008264934],"domain_scores_gemma":[0.9998869,0.00002360357,0.00002270249,0.00001894718,0.0000170246,0.00003083731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001418051,0.0001242459,0.00124801,0.0001991665,0.00004098826,0.0004444373,0.00007682778,0.0002635829,0.9828936,0.002873275,0.0002265311,0.01019122],"study_design_scores_gemma":[0.0001265436,0.0007223955,0.01082153,0.00002029556,0.0001518671,0.001136996,0.0001947306,0.002947444,0.9720201,0.00124817,0.01058952,0.00002023308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803773,0.007323328,0.005634855,0.0006343726,0.0001577664,0.00004694713,0.0003111433,0.0001584688,0.005355831],"genre_scores_gemma":[0.9955315,0.00123664,0.0008077924,0.0000502632,0.00001610319,0.00001798261,0.0001816267,0.00001188657,0.002146221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002466521,"threshold_uncertainty_score":0.008251369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006655891821484856,"score_gpt":0.2879604279152671,"score_spread":0.2813045360937823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}