{"id":"W2805091853","doi":"10.1111/mmi.14000","title":"The lytic transglycosylase MltB connects membrane homeostasis and <i>in vivo</i> fitness of <i>Acinetobacter baumannii</i>","year":2018,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; University of Michigan; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust; Wellcome","keywords":"Acinetobacter baumannii; Biology; Microbiology; Virulence; Pilus; Lytic cycle; Regulon; Peptidoglycan; Cell envelope; Pathogen; Gene; Mutant; Genetics; Bacteria; Pseudomonas aeruginosa","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001172745,0.0003544093,0.0001715114,0.0001525765,0.0001378584,0.0005333466,0.0001763717,0.0002689996,0.0006306391],"category_scores_gemma":[0.0001714422,0.0001206867,0.0001489004,0.0001208529,0.0002616799,0.0003281964,0.0003124657,0.0004360884,0.0001992418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004186769,"about_ca_system_score_gemma":0.0002199035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008047386,"about_ca_topic_score_gemma":0.0004971097,"domain_scores_codex":[0.9998479,0.00003368928,0.00001033451,0.000028643,0.00004189905,0.00003744305],"domain_scores_gemma":[0.9998654,0.00001432631,0.00006132997,0.00001352372,0.00001863559,0.00002670566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000402392,0.000005993134,0.0003400721,0.000009809968,0.00000178827,0.00001940483,0.000007054436,0.00005923682,0.9988379,0.00007812203,0.00001335643,0.0005871279],"study_design_scores_gemma":[0.000005100231,0.0001680791,0.01276165,0.000006631787,0.00001047912,0.0002726889,0.00005730493,0.001499713,0.983941,0.0001842143,0.001088383,0.000004799661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931131,0.0008015552,0.004682332,0.0002456708,0.00001470625,0.000008446565,0.0001749647,0.0001162518,0.0008429111],"genre_scores_gemma":[0.9982724,0.0002598018,0.0009462279,0.00003604764,0.0000034535,0.000004358872,0.0001344478,0.00001073389,0.0003325198],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008047386,"threshold_uncertainty_score":0.003037751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00479856755597106,"score_gpt":0.2191828470708182,"score_spread":0.2143842795148471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}