{"id":"W2805091853","doi":"10.1111/mmi.14000","title":"The lytic transglycosylase MltB connects membrane homeostasis and <i>in vivo</i> fitness of <i>Acinetobacter baumannii</i>","year":2018,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; University of Michigan; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust; Wellcome","keywords":"Acinetobacter baumannii; Biology; Microbiology; Virulence; Pilus; Lytic cycle; Regulon; Peptidoglycan; Cell envelope; Pathogen; Gene; Mutant; Genetics; Bacteria; Pseudomonas aeruginosa","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002750642,0.0002437613,0.0003149167,0.00005515037,0.00009254517,0.00002336539,0.0003177746,0.0002536314,0.00003688014],"category_scores_gemma":[0.00008773265,0.0001917842,0.00009115782,0.0001338272,0.0009508473,0.000004814256,0.0001192501,0.0001020962,0.000007159272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001282889,"about_ca_system_score_gemma":0.00005549728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001972271,"about_ca_topic_score_gemma":0.000248691,"domain_scores_codex":[0.9984524,0.0001862935,0.0003891389,0.0004858876,0.00004955412,0.0004367311],"domain_scores_gemma":[0.9991048,0.0000548241,0.0001320452,0.0005330827,0.0001121773,0.00006304486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004609506,0.00003930708,0.0011224,0.00003766255,0.00006401767,0.00001609165,0.0000386738,0.000002504767,0.9970871,0.0001263327,0.0006580363,0.0003469694],"study_design_scores_gemma":[0.0009288187,0.0003770828,0.0008522265,0.00003289787,0.00002632694,0.0000949667,0.00004837451,0.000005607873,0.9540403,0.00003801713,0.04333678,0.0002185856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958071,0.002460511,0.0004132036,0.0002700028,0.0001993639,0.000275149,0.0000864683,0.000008264279,0.0004799117],"genre_scores_gemma":[0.9981811,0.0006525684,0.0002518505,0.0005580753,0.00006764278,0.000008023175,0.000058079,0.0000327302,0.0001899136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04304674,"threshold_uncertainty_score":0.7820732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00479856755597106,"score_gpt":0.2191828470708182,"score_spread":0.2143842795148471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}