{"id":"W2805307061","doi":"10.1136/thoraxjnl-2017-210739","title":"Immunomodulatory innate defence regulator (IDR) peptide alleviates airway inflammation and hyper-responsiveness","year":2018,"lang":"en","type":"article","venue":"Thorax","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Respiratory Research Network; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Reseau canadien de recherche respiratoire; Children's Hospital Research Institute of Manitoba; Manitoba Health Research Council","keywords":"Immunology; Medicine; Bronchoalveolar lavage; Inflammation; Cytokine; Tumor necrosis factor alpha; Chemokine; Proinflammatory cytokine; Lung; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001318318,0.0004102595,0.0003471957,0.0001527229,0.00007649173,0.000207845,0.0002088737,0.0003320043,0.001259452],"category_scores_gemma":[0.00009032973,0.0001062342,0.0001739122,0.00007510812,0.0002608292,0.0001520282,0.0001551358,0.0008646828,0.0002959876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001358054,"about_ca_system_score_gemma":0.0001351161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007082523,"about_ca_topic_score_gemma":0.0001581301,"domain_scores_codex":[0.9999034,0.0000173574,0.000008277193,0.0000173809,0.00002739638,0.00002614041],"domain_scores_gemma":[0.9999174,0.000009160939,0.00002807699,0.000008424319,0.000005934336,0.00003098293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003906015,0.0001633065,0.0001926398,0.00006103476,0.000003969848,0.000071735,0.000005337208,0.00004712098,0.9975447,0.0000200969,0.0000295697,0.00146987],"study_design_scores_gemma":[0.0002135604,0.007313348,0.01120808,0.00001855725,0.00004270523,0.0009986438,0.00004470053,0.0007502415,0.976329,0.00005051644,0.003022762,0.000007883094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974506,0.001239556,0.0005341891,0.00007346425,0.00003180021,0.00002799056,0.0001053405,0.00005405292,0.0004829811],"genre_scores_gemma":[0.9963661,0.000797528,0.001024704,0.00009347039,0.00002629583,0.00004050904,0.0002479012,0.000009799973,0.00139367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001259452,"threshold_uncertainty_score":0.004213274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01243328177225815,"score_gpt":0.2330485812618497,"score_spread":0.2206152994895915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}