{"id":"W2805322110","doi":"10.1038/s41591-018-0059-x","title":"The human heart contains distinct macrophage subsets with divergent origins and functions","year":2018,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":687,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; U.S. Department of Veterans Affairs","keywords":"CCR2; Macrophage; Biology; Monocyte; Immune system; Immunology; Population; Cell biology; Medicine; Chemokine; Genetics; In vitro; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003167414,0.0001684905,0.0003136935,0.00005801995,0.0006850786,0.00001703238,0.00005557004,0.0001523887,0.000109447],"category_scores_gemma":[0.0001055416,0.00007583069,0.00005770364,0.0002021878,0.000604831,0.00002897224,0.00003976952,0.0006004171,0.00001501333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007354886,"about_ca_system_score_gemma":0.00004306553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001361682,"about_ca_topic_score_gemma":0.0002588384,"domain_scores_codex":[0.9988495,0.00003010421,0.0001879679,0.0002685251,0.0004042613,0.0002596256],"domain_scores_gemma":[0.999087,0.00008840216,0.00005129247,0.0003290179,0.0002368085,0.0002074952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002093516,0.0003065772,0.514631,0.0002985074,0.0009855829,0.0001665458,0.002444187,0.00000315335,0.2278903,0.01201334,0.2250676,0.01409961],"study_design_scores_gemma":[0.002894274,0.001393217,0.5213571,0.0003286768,0.0003839032,0.0003192019,0.0004365963,0.0001170026,0.001133719,0.00005514041,0.4714306,0.0001505899],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789852,0.004993737,0.000167392,0.009199169,0.0008667826,0.0003617758,0.00001227573,0.00006475626,0.005348849],"genre_scores_gemma":[0.9941075,0.0001123016,0.00008974879,0.001128776,0.002129907,0.000008102371,0.00004100246,0.00002260397,0.002360026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.246363,"threshold_uncertainty_score":0.5269139,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01035774720450567,"score_gpt":0.2927005959135708,"score_spread":0.2823428487090652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}