{"id":"W2805428376","doi":"10.1016/j.atherosclerosissup.2018.04.097","title":"High Density Lipoprotein Mediated Protection of Macrophages against Apoptosis Requires Scavenger Receptor Class B Type 1 Activity and Sphingosine-1-Phosphate","year":2018,"lang":"en","type":"article","venue":"Atherosclerosis Supplements","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"AMPK; Skeletal muscle; Internal medicine; Endocrinology; PI3K/AKT/mTOR pathway; Autophagy; Oxidative phosphorylation; mTORC1; Mechanistic target of rapamycin; Glycolysis; AMP-activated protein kinase; Inflammation; Protein kinase A; Medicine; Biology; Kinase; Biochemistry; Metabolism; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003368242,0.0004112392,0.000318925,0.0003727171,0.0002203394,0.0003712403,0.0002341901,0.0003550058,0.001811921],"category_scores_gemma":[0.0002226419,0.0001711002,0.0003266484,0.0001752217,0.000265718,0.0002997486,0.0003155732,0.0006528915,0.0005968755],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002411967,"about_ca_system_score_gemma":0.0003722065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005558358,"about_ca_topic_score_gemma":0.001046938,"domain_scores_codex":[0.9998158,0.00004622833,0.00002173653,0.00001746266,0.00003771733,0.00006126001],"domain_scores_gemma":[0.9997547,0.00004426782,0.0000408801,0.00004389133,0.00006351113,0.00005271995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002062616,0.0001168574,0.000360695,0.0000880822,0.00001779879,0.0001221124,0.00004510148,0.00003444831,0.9924793,0.0002234435,0.0001223278,0.004327164],"study_design_scores_gemma":[0.0001762094,0.0008046933,0.006846213,0.00001743539,0.00003669438,0.0003074496,0.00007714557,0.0003979619,0.9884287,0.0001865635,0.00271506,0.000006125547],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871284,0.005140008,0.003862585,0.0006743038,0.0001409894,0.00004398766,0.0003228921,0.000133808,0.002553051],"genre_scores_gemma":[0.9916211,0.001288798,0.002230316,0.0001112347,0.00003544254,0.00005198257,0.0004793709,0.00001256724,0.004169057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001811921,"threshold_uncertainty_score":0.006061494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01972273527605521,"score_gpt":0.2602776359058928,"score_spread":0.2405549006298376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}