{"id":"W2805428376","doi":"10.1016/j.atherosclerosissup.2018.04.097","title":"High Density Lipoprotein Mediated Protection of Macrophages against Apoptosis Requires Scavenger Receptor Class B Type 1 Activity and Sphingosine-1-Phosphate","year":2018,"lang":"en","type":"article","venue":"Atherosclerosis Supplements","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"AMPK; Skeletal muscle; Internal medicine; Endocrinology; PI3K/AKT/mTOR pathway; Autophagy; Oxidative phosphorylation; mTORC1; Mechanistic target of rapamycin; Glycolysis; AMP-activated protein kinase; Inflammation; Protein kinase A; Medicine; Biology; Kinase; Biochemistry; Metabolism; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003373224,0.0002593253,0.0002610783,0.00007518996,0.0001912173,0.00004548306,0.0002240641,0.0002189887,0.0001885051],"category_scores_gemma":[0.000211128,0.000248531,0.00006762367,0.0002567409,0.0003213665,0.00002519576,0.0003514093,0.0001460137,0.00003791708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004883384,"about_ca_system_score_gemma":0.0000531753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001361382,"about_ca_topic_score_gemma":0.0002615485,"domain_scores_codex":[0.9981829,0.0001669825,0.0002947148,0.0005611192,0.0003606135,0.0004336709],"domain_scores_gemma":[0.9988834,0.00001838531,0.0002016287,0.0004605614,0.0003033694,0.000132675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004392796,0.0001221474,0.006155907,0.00006029869,0.0001114986,1.378017e-7,0.00006898357,9.127173e-7,0.9879504,0.00000359858,0.001403035,0.00368384],"study_design_scores_gemma":[0.0009349863,0.001095894,0.04605575,0.00006420588,0.00001455982,4.924613e-7,0.00002355957,0.00003399625,0.9498736,0.00001033392,0.001678078,0.0002145425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998427,0.00005379632,0.0001682565,0.0002016785,0.0002119265,0.0007137692,0.0001721747,0.00002717397,0.00002426364],"genre_scores_gemma":[0.9981177,0.0002991546,0.0009172474,0.00006272831,0.0001854931,0.00006716123,0.0001687393,0.00005534455,0.0001263981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03989984,"threshold_uncertainty_score":0.9999967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01972273527605521,"score_gpt":0.2602776359058928,"score_spread":0.2405549006298376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}