{"id":"W2805598131","doi":"10.1093/abbs/gmy063","title":"DNA methylation of a non-CpG island promoter represses &amp;lt;italic&amp;gt;NQO1&amp;lt;/italic&amp;gt; expression in rat arsenic-transformed lung epithelial cells","year":2018,"lang":"en","type":"article","venue":"Acta Biochimica et Biophysica Sinica","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; McGill University","keywords":"Molecular biology; DNA methylation; Methylation; CpG site; Promoter; Biology; Bisulfite sequencing; Carcinogenesis; Gene expression; Epigenetics; Reporter gene; Chemistry; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000480254,0.0007866457,0.0009330306,0.0002149129,0.0001788083,0.0001026391,0.0008760879,0.0006809361,0.0001243873],"category_scores_gemma":[0.0003345005,0.0007165417,0.0005134448,0.0004134417,0.0007959299,0.00006713304,0.0004539756,0.0003850926,0.00008746875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005517129,"about_ca_system_score_gemma":0.0001973317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003697297,"about_ca_topic_score_gemma":0.0004280714,"domain_scores_codex":[0.9955578,0.0003007204,0.001262469,0.001554371,0.0004675704,0.0008571101],"domain_scores_gemma":[0.9965825,0.0001614835,0.0007483473,0.001864149,0.0003750374,0.0002684685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009629674,0.0007155773,0.00006932823,0.0001393358,0.0001769025,0.000001032745,0.001047727,0.000006488272,0.9894444,0.00001940539,0.006903016,0.0005138568],"study_design_scores_gemma":[0.00168298,0.0003307056,0.0009883553,0.0002193546,0.0001268716,0.000006363606,0.00002210123,0.00002272027,0.950161,0.0003892545,0.04524537,0.0008049594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930375,0.0002715633,0.002222623,0.0005258034,0.0004941347,0.001069792,0.0007291156,0.00004652003,0.001602983],"genre_scores_gemma":[0.9888203,0.0005324048,0.006617855,0.0002800952,0.0008862605,0.0001258447,0.00173851,0.0001262449,0.0008724756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0392834,"threshold_uncertainty_score":0.9995286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01480256509037954,"score_gpt":0.2834520551644467,"score_spread":0.2686494900740671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}