{"id":"W2805598131","doi":"10.1093/abbs/gmy063","title":"DNA methylation of a non-CpG island promoter represses &amp;lt;italic&amp;gt;NQO1&amp;lt;/italic&amp;gt; expression in rat arsenic-transformed lung epithelial cells","year":2018,"lang":"en","type":"article","venue":"Acta Biochimica et Biophysica Sinica","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China; McGill University","keywords":"Molecular biology; DNA methylation; Methylation; CpG site; Promoter; Biology; Bisulfite sequencing; Carcinogenesis; Gene expression; Epigenetics; Reporter gene; Chemistry; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001095191,0.0002362198,0.0002140287,0.0001670454,0.00009096993,0.0001487322,0.0001523254,0.000140401,0.001561634],"category_scores_gemma":[0.0001033651,0.000143263,0.000207607,0.0001572127,0.0002180549,0.00009688749,0.0001277449,0.0003357231,0.0003360687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001961587,"about_ca_system_score_gemma":0.0001905585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001505528,"about_ca_topic_score_gemma":0.002029899,"domain_scores_codex":[0.9998459,0.00002104611,0.00001391562,0.00005852976,0.00003223903,0.00002843387],"domain_scores_gemma":[0.9998881,0.00002321072,0.00002860762,0.00001714134,0.00001902679,0.00002384192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002358963,0.000004234614,0.00009439218,0.000008616694,0.000001314926,0.000006887394,0.00000858378,0.00001048051,0.9995946,0.00001424735,0.000004313229,0.0002287601],"study_design_scores_gemma":[0.000005286333,0.000212648,0.008284522,0.000002590016,0.00001243477,0.00008313504,0.00002612567,0.0004888191,0.9901357,0.00001629989,0.0007297144,0.000002688414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938778,0.0006729233,0.004077868,0.0000403878,0.00001655174,0.00001776727,0.0005257404,0.00005614102,0.0007147946],"genre_scores_gemma":[0.9912707,0.000534198,0.00309652,0.0000203519,0.000006148869,0.00004000224,0.00127987,0.00001918256,0.003733081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001561634,"threshold_uncertainty_score":0.005224228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01480256509037954,"score_gpt":0.2834520551644467,"score_spread":0.2686494900740671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}