{"id":"W2805803332","doi":"10.14740/jocmr3383w","title":"Serum Free Light Chains in Neoplastic Monoclonal Gammopathies: Relative Under-Detection of Lambda Dominant Kappa/Lambda Ratio, and Underproduction of Free Lambda Light Chains, as Compared to Kappa Light Chains, in Patients With Neoplastic Monoclonal Gammopathies","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Medicine Research","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Immunoglobulin light chain; Immunofixation; Kappa; Serum protein electrophoresis; Lambda; Monoclonal; Bence Jones protein; Medicine; Molecular biology; Antibody; Monoclonal antibody; Physics; Immunology; Biology; Optics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005525026,0.0003327597,0.0002465349,0.002024211,0.0003077615,0.000579006,0.000235513,0.0004504646,0.001012451],"category_scores_gemma":[0.003632477,0.0002219696,0.0001537913,0.0008986896,0.0004261611,0.0005407216,0.0003785666,0.0003244291,0.0001890091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001754275,"about_ca_system_score_gemma":0.0001850196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004769128,"about_ca_topic_score_gemma":0.0003841672,"domain_scores_codex":[0.9995528,0.00008872146,0.000103752,0.00008309571,0.0001196813,0.00005194827],"domain_scores_gemma":[0.998145,0.0007116513,0.0006176884,0.00007493889,0.0002069358,0.0002438855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002141382,0.00001239877,0.9936981,0.00002407482,0.00001479569,0.001539945,0.00008499678,0.00004452249,0.001897232,0.00001494,0.00003219386,0.002422608],"study_design_scores_gemma":[0.00001093727,0.0003404067,0.9593422,0.00002433437,0.00008778743,0.0357181,0.0003752531,0.0005351627,0.003065494,0.0001018501,0.0003888091,0.000009712768],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984579,0.0009218624,0.0001593417,0.00001930847,0.00000408572,0.000002889158,0.00003640673,0.000006563816,0.0003916501],"genre_scores_gemma":[0.9996899,0.0001190642,0.0001009777,0.00000952254,0.000006331648,0.000001575989,0.00003039597,0.000001539,0.00004070644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002024211,"threshold_uncertainty_score":0.003386974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03565192518875742,"score_gpt":0.3698726174035609,"score_spread":0.3342206922148035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}