{"id":"W2805814235","doi":"10.1128/msphere.00245-18","title":"Sublingual Adjuvant Delivery by a Live Attenuated Vibrio cholerae-Based Antigen Presentation Platform","year":2018,"lang":"en","type":"article","venue":"mSphere","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Science Centre for Human and Animal Health; Government of Canada; Canadian Food Inspection Agency","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Vibrio cholerae; Immunogenicity; Adjuvant; Cholera toxin; Antigen; Microbiology; Cholera; Antigen presentation; Immune system; Cholera vaccine; Virology; Biology; Vaccination; Heterologous; Immunology; Medicine; T cell; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001160037,0.0001831321,0.0001592959,0.00002511527,0.0001751009,0.00006856288,0.000212992,0.0001362021,0.0002827175],"category_scores_gemma":[0.0001075973,0.000169767,0.00007330516,0.000112552,0.0001968794,0.00001206785,0.000155411,0.00009161131,0.0001686831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003063438,"about_ca_system_score_gemma":0.0001406531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002584487,"about_ca_topic_score_gemma":0.0003181191,"domain_scores_codex":[0.9987595,0.00004848556,0.0001886692,0.0003932772,0.0002239916,0.000386055],"domain_scores_gemma":[0.9991971,0.00001484889,0.0000771369,0.000305188,0.0003016769,0.0001040218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003196257,0.00006768349,0.005696575,0.00001745956,0.0001043989,0.000006025406,0.0001343237,0.000007237274,0.9378891,0.000001097707,0.05186887,0.003887595],"study_design_scores_gemma":[0.001760398,0.000886908,0.02445078,0.00003373263,0.00001776925,0.000004445004,0.0002798078,0.0005813472,0.8721034,0.000009684718,0.09953761,0.0003341032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971222,0.0007393493,0.0003918596,0.0002067307,0.0001369584,0.0002778449,0.0001030238,0.00003402541,0.0009880357],"genre_scores_gemma":[0.9968325,0.0001281782,0.0005140292,0.0003024034,0.0005611455,0.00003120339,0.0006462928,0.00003177534,0.000952506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06578569,"threshold_uncertainty_score":0.6922895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524288183894542,"score_gpt":0.2792867965421963,"score_spread":0.2640439147032509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}