{"id":"W2805814235","doi":"10.1128/msphere.00245-18","title":"Sublingual Adjuvant Delivery by a Live Attenuated Vibrio cholerae-Based Antigen Presentation Platform","year":2018,"lang":"en","type":"article","venue":"mSphere","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Science Centre for Human and Animal Health; Government of Canada; Canadian Food Inspection Agency","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Vibrio cholerae; Immunogenicity; Adjuvant; Cholera toxin; Antigen; Microbiology; Cholera; Antigen presentation; Immune system; Cholera vaccine; Virology; Biology; Vaccination; Heterologous; Immunology; Medicine; T cell; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001164197,0.0003209224,0.0001823379,0.000130576,0.0000871387,0.0002262731,0.0001794664,0.0003013478,0.0005660497],"category_scores_gemma":[0.00008578475,0.000126538,0.0001660579,0.00007659749,0.0001708572,0.0001875265,0.0002513391,0.0004172553,0.0003237607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002875976,"about_ca_system_score_gemma":0.0002439731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003231344,"about_ca_topic_score_gemma":0.0004757878,"domain_scores_codex":[0.9999405,0.000008689882,0.000004438738,0.00001513201,0.00001517903,0.00001607473],"domain_scores_gemma":[0.9999423,0.000007088045,0.00002514956,0.000005250501,0.000006924068,0.00001328009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007130433,0.000007913328,0.00001401319,0.000009469533,7.155306e-7,0.000008450633,0.000003085648,0.00006893178,0.9994456,0.00005779422,0.000009261636,0.0003676379],"study_design_scores_gemma":[0.000008109103,0.0002055242,0.0001702002,0.000002368392,0.000005845098,0.0000501301,0.000003985231,0.0005953645,0.9975497,0.00002508335,0.001381598,0.000002124844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724557,0.0009048549,0.02487764,0.0001540634,0.00005265301,0.00007048022,0.0001672647,0.000149535,0.001167796],"genre_scores_gemma":[0.9749765,0.0007947359,0.02067137,0.0000899627,0.00001489962,0.00006107068,0.0002020784,0.00004459325,0.003144848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005660497,"threshold_uncertainty_score":0.002086639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524288183894542,"score_gpt":0.2792867965421963,"score_spread":0.2640439147032509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}