{"id":"W2805959943","doi":"10.1101/339861","title":"Transmission cycles generate diversity in pathogenic viruses","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Transmission (telecommunications); Virus; Population bottleneck; Bottleneck; Genetics; Mutation; Genetic diversity; Viral evolution; Population; Host (biology); Gene; Evolutionary biology; Virology; Genome; Allele; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000596515,0.000205594,0.0002778158,0.0005482109,0.0003841878,0.000675054,0.0003924424,0.0004880213,0.0007721153],"category_scores_gemma":[0.002556728,0.0002766744,0.0003101229,0.0001881973,0.0004213577,0.0006890272,0.0005105216,0.0003894032,0.0001065431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006560407,"about_ca_system_score_gemma":0.0001836105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006508906,"about_ca_topic_score_gemma":0.0004261429,"domain_scores_codex":[0.9998227,0.00004441084,0.000008222092,0.00003692706,0.00005169346,0.00003604613],"domain_scores_gemma":[0.9986625,0.0007068287,0.000297197,0.0001101646,0.0001102935,0.000113168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0005278031,0.0002988949,0.107801,0.0001487988,0.0001925382,0.001790272,0.0005907491,0.4022385,0.3930419,0.06532904,0.0008086304,0.02723191],"study_design_scores_gemma":[0.00003114608,0.0001634798,0.03035915,0.00001366278,0.00003812379,0.0007718545,0.0001564055,0.905831,0.03104159,0.03060623,0.0009436876,0.0000435659],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902298,0.00007248868,0.009103399,0.00005060435,0.000003071984,0.000004388612,0.00002432385,0.00002383347,0.00048815],"genre_scores_gemma":[0.9990127,0.00002727694,0.0008032456,0.00000716797,0.000002159526,0.000003315705,0.00001931198,0.000004958337,0.000119807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007721153,"threshold_uncertainty_score":0.004759908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01666267499224382,"score_gpt":0.2326123571688391,"score_spread":0.2159496821765953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}