{"id":"W2806036636","doi":"10.1186/s40168-018-0479-3","title":"Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative","year":2018,"lang":"en","type":"review","venue":"Microbiome","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Public Health Ontario; University of Toronto; Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; Canadian Institutes of Health Research; Novo Nordisk Fonden; University of Toronto; University of North Carolina at Chapel Hill; National Institutes of Health; Lundbeckfonden; Ewha Womans University; University of Bristol; National Institute for Health and Care Research; National Heart, Lung, and Blood Institute; Hospital for Sick Children; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust","keywords":"Genome-wide association study; Biology; Metagenomics; Microbiome; Computational biology; Human Microbiome Project; Human microbiome; Population; Genomics; Genetic association; Genetics; Genome; Single-nucleotide polymorphism; Genotype; Gene; Environmental health; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00152809,0.0007419247,0.0043694,0.0006371977,0.0003229641,0.00005012052,0.0008793779,0.0008081287,0.000259658],"category_scores_gemma":[0.0001059915,0.0004857443,0.004462151,0.001543612,0.000439027,0.000005393773,0.0004863353,0.0002910062,0.0001237746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003047869,"about_ca_system_score_gemma":0.000376243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003857387,"about_ca_topic_score_gemma":0.0001706883,"domain_scores_codex":[0.9957906,0.0008272327,0.001615599,0.0009770516,0.0001679967,0.0006215314],"domain_scores_gemma":[0.9955022,0.0001811511,0.00236286,0.001218433,0.0006492564,0.00008615135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000856046,0.0001631239,0.000005953314,0.003825114,0.7048827,0.000002852853,0.0005158162,4.861991e-7,0.2637878,0.00001506008,0.02627248,0.0005200808],"study_design_scores_gemma":[0.000118982,0.0001375508,0.00001063449,0.00008586741,0.2739815,0.000008407705,0.0000667842,3.189561e-8,0.001746372,0.000003231502,0.7234675,0.000373175],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006419598,0.9931963,0.00001227484,0.0001010628,0.000199279,0.001038101,0.004640174,0.00001586266,0.0001549945],"genre_scores_gemma":[0.0002665538,0.9879824,0.0001045534,0.0005933295,0.0002692823,0.0001060554,0.006614511,0.00008375534,0.003979561],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.697195,"threshold_uncertainty_score":0.9997594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.23421497875463,"score_gpt":0.4156677919632596,"score_spread":0.1814528132086296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}