{"id":"W2806036636","doi":"10.1186/s40168-018-0479-3","title":"Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative","year":2018,"lang":"en","type":"review","venue":"Microbiome","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":186,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Public Health Ontario; University of Toronto; Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; Canadian Institutes of Health Research; Novo Nordisk Fonden; University of Toronto; University of North Carolina at Chapel Hill; National Institutes of Health; Lundbeckfonden; Ewha Womans University; University of Bristol; National Institute for Health and Care Research; National Heart, Lung, and Blood Institute; Hospital for Sick Children; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust","keywords":"Genome-wide association study; Biology; Metagenomics; Microbiome; Computational biology; Human Microbiome Project; Human microbiome; Population; Genomics; Genetic association; Genetics; Genome; Single-nucleotide polymorphism; Genotype; Gene; Environmental health; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1103566,0.00323994,0.005794546,0.008300119,0.001725008,0.004705222,0.0049683,0.002252123,0.005278426],"category_scores_gemma":[0.1306869,0.001960671,0.01335544,0.009278251,0.0008826707,0.001277198,0.008329742,0.003948125,0.0008982183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001543167,"about_ca_system_score_gemma":0.007441322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01043439,"about_ca_topic_score_gemma":0.01477331,"domain_scores_codex":[0.9159916,0.06884047,0.002531975,0.006134394,0.005616227,0.0008853755],"domain_scores_gemma":[0.8741916,0.07588137,0.006533214,0.03034116,0.008404036,0.004648626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01109343,0.0003380897,0.2494795,0.008208876,0.4554216,0.0009241276,0.000590161,0.02091968,0.003432493,0.008432051,0.08616143,0.1549985],"study_design_scores_gemma":[0.0117624,0.001735207,0.3062879,0.006256932,0.3079241,0.002425007,0.0005635138,0.1033911,0.00445676,0.08099248,0.1731732,0.001031372],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.1555505,0.1932119,0.4671905,0.03256731,0.004896823,0.00341909,0.1251586,0.0113952,0.006610151],"genre_scores_gemma":[0.3347764,0.02280428,0.507659,0.006871016,0.002187949,0.01000161,0.1067567,0.006485351,0.00245779],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.1103566,"threshold_uncertainty_score":0.5836287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.23421497875463,"score_gpt":0.4156677919632596,"score_spread":0.1814528132086296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}