{"id":"W2806365862","doi":"10.1186/s12900-018-0086-3","title":"Functional insights from proteome-wide structural modeling of Treponema pallidum subspecies pallidum, the causative agent of syphilis","year":2018,"lang":"en","type":"article","venue":"BMC Structural Biology","topic":"Syphilis Diagnosis and Treatment","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Treponema; Proteome; Virulence; Biology; Computational biology; Genetics; Syphilis; Genome; Gene; Microbiology; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007765353,0.001327915,0.0006867979,0.0007027464,0.0006760306,0.00112905,0.000943283,0.001120768,0.001747097],"category_scores_gemma":[0.001300237,0.0004295095,0.00161053,0.0004595603,0.0002954527,0.001027078,0.0004772582,0.0008239564,0.0006468937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007461957,"about_ca_system_score_gemma":0.00108371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004066679,"about_ca_topic_score_gemma":0.003708347,"domain_scores_codex":[0.9998121,0.00005111889,0.0000108094,0.00004987476,0.00004898464,0.00002718894],"domain_scores_gemma":[0.9995782,0.0001886177,0.00006372303,0.00004712118,0.00007787171,0.00004435736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.000597537,0.0003193482,0.01964535,0.0006733715,0.000397449,0.001071452,0.0005224255,0.8284797,0.1263816,0.006439671,0.002889763,0.01258237],"study_design_scores_gemma":[0.0000192859,0.00005619494,0.001587117,0.00001668861,0.00003541146,0.00009468442,0.00005852205,0.9915069,0.004462451,0.001177238,0.0009727948,0.0000128885],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9124922,0.0009911776,0.07322691,0.0007129398,0.00007063373,0.00007203373,0.003475297,0.003928882,0.005029964],"genre_scores_gemma":[0.9530495,0.0007188222,0.03935435,0.0001170839,0.00002213712,0.00007712084,0.005503176,0.0005837606,0.0005740193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004066679,"threshold_uncertainty_score":0.008086026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06668022112420356,"score_gpt":0.2978571101213261,"score_spread":0.2311768889971225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}