{"id":"W2806371526","doi":"10.1016/j.jaut.2018.04.004","title":"Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint","year":2018,"lang":"en","type":"article","venue":"Journal of Autoimmunity","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Janssen Research and Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; Knut och Alice Wallenbergs Stiftelse; Boehringer Ingelheim Fonds; Sveriges Läkarförbund; Vetenskapsrådet; Bloorview Research Institute","keywords":"Synovial fluid; Epitope; T cell; Immunology; Immune system; Flow cytometry; Citrullination; Citrulline; Antigen; Molecular biology; Chemistry; Biology; Medicine; Pathology; Biochemistry; Arginine; Amino acid; Osteoarthritis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001418284,0.0002978542,0.0003316809,0.000960255,0.00036902,0.0006037683,0.0002121585,0.0004757938,0.004771485],"category_scores_gemma":[0.0003049989,0.0003160486,0.0002312014,0.0002507915,0.0001994535,0.0003208585,0.0003054302,0.0005451691,0.0006897552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001817939,"about_ca_system_score_gemma":0.0001386942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005667277,"about_ca_topic_score_gemma":0.0007352715,"domain_scores_codex":[0.9997751,0.00002457746,0.00001399889,0.00005797079,0.00003500108,0.00009334688],"domain_scores_gemma":[0.9998592,0.00002214128,0.00002382791,0.00001693149,0.00003551025,0.00004233266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009084528,0.00009224064,0.01572084,0.0001809534,0.00004641318,0.0009900465,0.000281994,0.0001074326,0.9641934,0.0004421192,0.0004639498,0.01657214],"study_design_scores_gemma":[0.0005896214,0.00229342,0.5830054,0.0002972242,0.0005914714,0.01805137,0.002840945,0.002870229,0.3443192,0.003035506,0.04202105,0.00008466544],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991487,0.004636521,0.001036578,0.00008456568,0.00008352238,0.00001227824,0.0001080715,0.00007129116,0.002480168],"genre_scores_gemma":[0.9948465,0.00100056,0.0004825526,0.00009396495,0.0001134139,0.00001841826,0.0001284361,0.00002341664,0.00329279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004771485,"threshold_uncertainty_score":0.01596218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05895076353298537,"score_gpt":0.3181407435393254,"score_spread":0.25918998000634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}