{"id":"W2806544610","doi":"10.1200/jco.2017.76.7228","title":"Dasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: Results of Children’s Oncology Group Trial AALL0622","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":250,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"National Cancer Institute","keywords":"Medicine; Dasatinib; Imatinib; Cumulative incidence; Internal medicine; Hematopoietic stem cell transplantation; Chemotherapy; Acute lymphocytic leukemia; Philadelphia chromosome; Transplantation; Oncology; Leukemia; Surgery; Lymphoblastic Leukemia; Myeloid leukemia; Chromosomal translocation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003404539,0.0004819033,0.003618407,0.0005726925,0.00008336984,0.00001747505,0.0005165626,0.0012664,0.00004983515],"category_scores_gemma":[0.006580433,0.00033756,0.0004238955,0.0005719652,0.002507446,0.0002420146,0.0002531933,0.002272555,0.00001391051],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003377578,"about_ca_system_score_gemma":0.01020279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004051775,"about_ca_topic_score_gemma":0.0003267432,"domain_scores_codex":[0.9918674,0.001001367,0.004540141,0.0007701386,0.001048477,0.0007724942],"domain_scores_gemma":[0.9900479,0.00255428,0.003819788,0.0004816466,0.002301405,0.0007949788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8982871,0.003090178,0.06004242,0.00005786063,0.002627683,0.001517797,0.001819467,0.000009386963,0.0004785395,0.00002700921,0.003858636,0.02818396],"study_design_scores_gemma":[0.4191803,0.1158306,0.4535972,0.001227046,0.0007211037,0.007737486,0.0003567925,0.0005382117,0.0003145901,0.00003444529,0.0002093376,0.0002528105],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920275,0.0002013171,0.0002624842,0.004333669,0.0009322471,0.001712934,0.00006960193,0.00001871864,0.0004415211],"genre_scores_gemma":[0.9895511,0.001835488,0.002161526,0.002815405,0.00346393,0.00001790205,0.00004085274,0.00007173832,0.00004209418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4791068,"threshold_uncertainty_score":0.9999077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03012673645879117,"score_gpt":0.3770404011580003,"score_spread":0.3469136646992091,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}