{"id":"W2806546282","doi":"10.1007/978-1-4939-7804-5_9","title":"Mass Spectrometry-Based Proteomics","year":2018,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Concordia University","funders":"Génome Québec; Genome Canada","keywords":"Proteomics; Bottom-up proteomics; Mass spectrometry; Chemistry; Chromatography; Quantitative proteomics; Proteolytic enzymes; Protein mass spectrometry; Computational biology; Tandem mass spectrometry; Biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001906667,0.001797216,0.001217779,0.002982116,0.001082182,0.002972492,0.002651294,0.002207737,0.005775856],"category_scores_gemma":[0.001466919,0.0007349205,0.001037607,0.00196522,0.001100722,0.002637085,0.002310389,0.002710806,0.01049162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001137831,"about_ca_system_score_gemma":0.001367127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006046428,"about_ca_topic_score_gemma":0.0007646453,"domain_scores_codex":[0.9969569,0.0003775078,0.000149263,0.0007269784,0.001598008,0.0001912758],"domain_scores_gemma":[0.9993621,0.0001017199,0.00008006637,0.0001447621,0.0002421231,0.00006935818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001841739,0.0001391831,0.0006211528,0.0008544403,0.0001683976,0.000193139,0.00006941566,0.0002105875,0.8965597,0.01173531,0.01218677,0.07707772],"study_design_scores_gemma":[0.0000531012,0.0001892031,0.002288704,0.0001209693,0.00008158986,0.001860934,0.00005061847,0.006475041,0.8268053,0.009529451,0.1524431,0.0001019388],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.04991666,0.06404249,0.7966053,0.005967919,0.004596292,0.001095852,0.005858433,0.01071532,0.06120172],"genre_scores_gemma":[0.2401634,0.05127858,0.6031042,0.007489753,0.002246701,0.001012966,0.01123757,0.001267054,0.0821998],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.005775856,"threshold_uncertainty_score":0.01932222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01960380291448226,"score_gpt":0.4029376064021088,"score_spread":0.3833338034876265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}