{"id":"W2806582652","doi":"10.1002/bit.26735","title":"Broadened glycosylation patterning of heterologously produced erythromycin","year":2018,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Glycosylation; Bacillus subtilis; Erythromycin; Escherichia coli; Biochemistry; Natural product; Antibiotics; Biology; Microbiology; Heterologous; Chemistry; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007412987,0.0001768574,0.0001121781,0.00008572848,0.00005761664,0.0002713579,0.0001524119,0.0001704931,0.0005743179],"category_scores_gemma":[0.0001141566,0.00009179856,0.00009686162,0.0001302132,0.0001353137,0.0001641333,0.0002128157,0.000352339,0.0002281916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002345235,"about_ca_system_score_gemma":0.0001096899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003524765,"about_ca_topic_score_gemma":0.0005912309,"domain_scores_codex":[0.9999313,0.00001221764,0.000007379097,0.00001651828,0.00001827667,0.00001428665],"domain_scores_gemma":[0.999938,0.00001027075,0.00002283326,0.00001129907,0.000007546534,0.000009960104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001933076,0.00000639528,0.00004263612,0.000007229083,6.4511e-7,0.00003629312,0.000008569795,0.0001362088,0.9987765,0.0001832371,0.00001036702,0.000772717],"study_design_scores_gemma":[0.00000349067,0.00005649513,0.0004170059,0.000002017119,0.000002251834,0.00006060065,0.000009340022,0.0009827296,0.9966047,0.00002806512,0.00183022,0.000003083445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913275,0.0001658971,0.005341853,0.00004058943,0.00001361641,0.00001496495,0.0001044379,0.00003877845,0.002952527],"genre_scores_gemma":[0.9922007,0.0002420744,0.005461364,0.00002497504,0.000003126473,0.00000842204,0.0001211677,0.00002405452,0.00191427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005743179,"threshold_uncertainty_score":0.001921296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007908805601797811,"score_gpt":0.1998088391438403,"score_spread":0.1919000335420425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}