{"id":"W2806895491","doi":"10.1111/cts.12562","title":"Anisomycin Activates Utrophin Upregulation Through a p38 Signaling Pathway","year":2018,"lang":"en","type":"article","venue":"Clinical and Translational Science","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agricultural Research Institute of Ontario; University of Ottawa","funders":"Genome British Columbia; National Institutes of Health; Canadian Institutes of Health Research; Genome Canada; Ontario Genomics; Ontario Genomics Institute","keywords":"Utrophin; Duchenne muscular dystrophy; Anisomycin; Dystrophin; Downregulation and upregulation; Medicine; Muscular dystrophy; Myocyte; Biology; Cell biology; Internal medicine; Genetics; Gene; Kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003190803,0.00006809325,0.00007452354,0.00001284072,0.0002617572,0.00001682481,0.0001091689,0.00007898463,0.00004125253],"category_scores_gemma":[0.00008701647,0.00005614019,0.00004213589,0.0001121302,0.001448943,0.00001932937,0.00002814492,0.00005353868,0.000007181745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":9.014801e-7,"about_ca_system_score_gemma":0.00009625212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005598984,"about_ca_topic_score_gemma":0.000007466804,"domain_scores_codex":[0.9992076,0.00003692994,0.0001750141,0.0003340186,0.0001075894,0.0001388978],"domain_scores_gemma":[0.9996768,0.00004536045,0.000040666,0.0001009977,0.00007707983,0.00005909683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000271284,0.0001012093,0.03119419,0.000005567872,0.00001448473,3.021003e-7,0.0001196235,0.0000684904,0.9428795,0.01072259,0.00006023153,0.01456251],"study_design_scores_gemma":[0.001332288,0.0008278962,0.7286255,0.00001900893,0.00001280948,0.000004897504,0.00005323235,0.00130548,0.1876097,0.07148589,0.008416198,0.0003070425],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927214,0.0001102248,0.005180405,0.0004669824,0.0001135531,0.000065844,0.000004961171,0.000007731821,0.001328881],"genre_scores_gemma":[0.9972143,0.0000253604,0.002021202,0.0003815555,0.0002989322,0.000003073574,0.00001722755,0.000003318254,0.00003502566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7552698,"threshold_uncertainty_score":0.5338693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03367824689102979,"score_gpt":0.3415573914475339,"score_spread":0.3078791445565041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}