{"id":"W2806926343","doi":"10.1016/j.immuni.2018.04.012","title":"The Tumor Necrosis Factor Superfamily Member RANKL Suppresses Effector Cytokine Production in Group 3 Innate Lymphoid Cells","year":2018,"lang":"en","type":"article","venue":"Immunity","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":88,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Dental and Craniofacial Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; Digestive Diseases Research Core Center, University of Chicago; Crohn's and Colitis Foundation of America","keywords":"RANKL; Innate lymphoid cell; Biology; CCL20; C-C chemokine receptor type 6; Cytokine; Tumor necrosis factor alpha; Immunology; Cancer research; Cell biology; Cytokine receptor; Receptor; Chemokine; Innate immune system; Activator (genetics); Chemokine receptor; Inflammation; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002540488,0.0005195014,0.0003190429,0.0003347911,0.0002435132,0.0005691688,0.0001713556,0.0002956089,0.002309802],"category_scores_gemma":[0.0002158617,0.000135763,0.000316142,0.000171528,0.0003332191,0.0002783559,0.0003006338,0.001235995,0.0007597868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003409329,"about_ca_system_score_gemma":0.0007517668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007426731,"about_ca_topic_score_gemma":0.001780856,"domain_scores_codex":[0.9995628,0.00009701333,0.00002672188,0.00001981403,0.0001104848,0.0001831964],"domain_scores_gemma":[0.9997761,0.0000292254,0.00005629969,0.00003353899,0.00002568117,0.00007931159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006373058,0.00007103841,0.0003027671,0.0000468826,0.000004911251,0.00009642279,0.00002340147,0.0001025143,0.9960218,0.0001758858,0.0001882403,0.002329009],"study_design_scores_gemma":[0.0001108765,0.00109211,0.007947318,0.00001236718,0.00002762187,0.0003948837,0.0001430424,0.001045596,0.9839987,0.0003051053,0.004912282,0.00001024727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936146,0.001698883,0.001182308,0.0002790889,0.00005552958,0.00002255722,0.0003684876,0.0001602084,0.002618314],"genre_scores_gemma":[0.9949487,0.0004781687,0.0004340045,0.00007295858,0.00002358905,0.00002147863,0.0003846031,0.00001908671,0.003617261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002309802,"threshold_uncertainty_score":0.007727027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01584650975077945,"score_gpt":0.2339088030263959,"score_spread":0.2180622932756165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}