{"id":"W2807031272","doi":"10.1016/j.jcmgh.2018.04.008","title":"A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture","year":2018,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases","keywords":"Organoid; Biopsy; Medicine; Pathology; Biology; Cell biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002862792,0.0001885922,0.0003035741,0.00008556631,0.0001358054,0.00001162622,0.0001217948,0.0002718612,0.00001211075],"category_scores_gemma":[0.00003196431,0.000179019,0.00006451696,0.00004314073,0.0005593305,0.000006492258,0.0002316512,0.00009936907,6.541088e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005836836,"about_ca_system_score_gemma":0.00002224112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002019582,"about_ca_topic_score_gemma":0.00006574873,"domain_scores_codex":[0.9985796,0.0002069663,0.0002529773,0.0005208526,0.00007286423,0.0003667112],"domain_scores_gemma":[0.9993687,0.00001206959,0.0001044555,0.0002429581,0.0001524257,0.0001193706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004039663,0.00004752199,0.030088,0.0000842899,0.0001339763,0.00001330709,0.00008956055,3.006983e-7,0.9678859,0.0008989533,0.0002122662,0.0001419305],"study_design_scores_gemma":[0.00210536,0.003649566,0.00418368,0.00001100215,0.0001134795,0.0003916257,0.00005532864,0.0003722714,0.9832636,0.0008482084,0.004842547,0.0001633659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9281569,0.00137748,0.06963906,0.0003221635,0.00004695223,0.0003416321,0.00002564013,0.000006591117,0.0000836589],"genre_scores_gemma":[0.991696,0.0002698876,0.007196112,0.0003584724,0.00007346694,0.00003564151,0.0001621712,0.00002197102,0.0001862504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0635392,"threshold_uncertainty_score":0.7300182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0134503076537595,"score_gpt":0.2849501822736216,"score_spread":0.2714998746198621,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}